• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

CD6 Recombinant antibody, PBS Only

CD6 Uni-rAbTM Recombinant Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241965D11

Cat no : 84508-5-PBS

Print datasheet

Synonyms

TP120, T-cell differentiation antigen CD6, T12, Soluble CD6, CD6 molecule

验证数据展示

  • WB analysis of Jurkat using 84508-5-RR (same clone as 84508-5-PBS)

    WB analysis of Jurkat using 84508-5-RR (same clone as 84508-5-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 84508-5-RR (CD6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84508-5-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 84508-5-RR (same clone as 84508-5-PBS)

    IHC staining of human tonsillitis using 84508-5-RR (same clone as 84508-5-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 84508-5-RR (CD6 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84508-5-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 84508-5-RR (same clone as 84508-5-PBS)

    IHC staining of human tonsillitis using 84508-5-RR (same clone as 84508-5-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 84508-5-RR (CD6 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84508-5-PBS in a different storage buffer formulation.

产品信息

84508-5-PBS targets CD6 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen FusionProtein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name CD6 molecule
Synonyms TP120, T-cell differentiation antigen CD6, T12, Soluble CD6, CD6 molecule
Observed Molecular Weight140 kDa
GenBank Accession NumberBC033755
Gene Symbol CD6
Gene ID (NCBI) 923
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP30203
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD6 is a type I transmembrane glycoprotein that belongs to the scavenger receptor cysteine-rich superfamily (PMID: 21880988). It is composed of an extracellular region, which consists of three tandem SRCR domains, a transmembrane region, and a cytoplasmic tail devoid of intrinsic catalytic activity but harboring several phosphorylatable residues suitable for intracellular signal transduction (PMID: 38139340; 23711376). CD6 is expressed by T cells, medullary thymocytes, a subset of B cells and NK cells, and in some cells of the brain (PMID: 1919444; 21178331). CD6 plays a role in lymphocyte activation, proliferation, and survival processes via interaction with its endogenous ligands.