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Anti-Human CD6 Rabbit Recombinant Antibody, PBS Only

CD6 Uni-rAbTM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

241965C9

Cat no : 98223-1-PBS

Print datasheet

Synonyms

TP120, T-cell differentiation antigen CD6, T12, Soluble CD6, CD6 molecule

验证数据展示

  • FC experiment of human PBMCs using 98223-1-RR (same clone as 98223-1-PBS)

    FC experiment of human PBMCs using 98223-1-RR (same clone as 98223-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD6 Rabbit Recombinant Antibody (98223-1-RR, Clone: 241965C9) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with APC Anti-Human CD3 (OKT3) Mouse IgG2a Recombinant Antibody (APC-65569, Clone: OKT3). Cells were not fixed. This data was developed using the same antibody clone with 98223-1-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 98223-1-RR (same clone as 98223-1-PBS)

    FC experiment of human PBMCs using 98223-1-RR (same clone as 98223-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD6 Rabbit Recombinant Antibody (98223-1-RR, Clone: 241965C9) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98223-1-PBS in a different storage buffer formulation.

产品信息

98223-1-PBS targets CD6 in FC applications and shows reactivity with human samples.

Tested Applications FC Application Description
Tested Reactivity human
Immunogen Recombinant protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name CD6 molecule
Synonyms TP120, T-cell differentiation antigen CD6, T12, Soluble CD6, CD6 molecule
GenBank Accession NumberBC033755
Gene Symbol CD6
Gene ID (NCBI) 923
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP30203
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD6 is a type I transmembrane glycoprotein that belongs to the scavenger receptor cysteine-rich superfamily (PMID: 21880988). It is composed of an extracellular region, which consists of three tandem SRCR domains, a transmembrane region, and a cytoplasmic tail devoid of intrinsic catalytic activity but harboring several phosphorylatable residues suitable for intracellular signal transduction (PMID: 38139340; 23711376). CD6 is expressed by T cells, medullary thymocytes, a subset of B cells and NK cells, and in some cells of the brain (PMID: 1919444; 21178331). CD6 plays a role in lymphocyte activation, proliferation, and survival processes via interaction with its endogenous ligands.