验证数据展示
经过测试的应用
Positive FC detected in | Thrombin treated human peripheral blood platelets |
推荐稀释比
应用 | 推荐稀释比 |
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This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
PE-FcA65587 targets CD62P in FC applications and shows reactivity with human samples.
经测试应用 | FC Application Description |
经测试反应性 | human |
免疫原 | Human platelets 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | selectin P (granule membrane protein 140kDa, antigen CD62) |
别名 | P-selectin, GMRP, GMP-140, GMP140, GMP 140 |
计算分子量 | 830 aa, 91 kDa |
GenBank蛋白编号 | BC028067 |
基因名称 | CD62P |
Gene ID (NCBI) | 6403 |
偶联类型 | PE Fluorescent Dye |
最大激发/发射波长 | 496 nm, 565 nm / 578 nm |
形式 | Liquid |
纯化方式 | Protein A purification |
储存缓冲液 | PBS with 0.09% sodium azide and 0.5% BSA , pH 7.3 |
储存条件 | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
P-selectin, also known as GMP140 or CD62P, is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation, thrombosis, and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.
实验方案
Product Specific Protocols | |
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FC protocol for PE CD62P antibody PE-FcA65587 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |