验证数据展示
产品信息
27563-1-PBS targets CD64 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
Tested Applications | WB, IF/ICC, Indirect ELISA Application Description |
Tested Reactivity | human |
Immunogen | CD64 fusion protein Ag26727 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | Fc fragment of IgG, high affinity Ia, receptor (CD64) |
Synonyms | |
Calculated Molecular Weight | 374 aa, 43 kDa |
Observed Molecular Weight | 65-70 kDa, 43-45 kDa |
GenBank Accession Number | BC032634 |
Gene Symbol | FCGR1A |
Gene ID (NCBI) | 2209 |
ENSEMBL Gene ID | ENSG00000150337 |
RRID | AB_2880909 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | P12314 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Fcγ receptor comprise a multigene family of integral membrane glycoproteins that exhibit complex activation or inhibitory effects on cell functions after aggregation by complexed immunoglobulin G (IgG) (PMID: 17005690 ). CD64, also known as FcγRIA, is a high affinity receptor for the Fc region of IgG. It is expressed by monocytes/macrophages, activated neutrophils, dendritic cells, and early myeloid cells (PMID: 23293080; 19642859; 7680917). CD64 functions in both innate and adaptive immune responses. The calculated molecular weight of CD64 is 43 kDa, while the glycosylated CD64 has a higher apparent molecular weight.