Anti-Human CD70 Rabbit Recombinant Antibody, PBS Only

CD70 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98098-1-PBS

产品说明书

CloneNo. 241325D8

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

241325D8, CD27 L, CD27 ligand, CD27L, CD27-L

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


产品信息

98098-1-PBS targets CD70 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Recombinant Protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CD70 molecule
别名 241325D8, CD27 L, CD27 ligand, CD27L, CD27-L
计算分子量 21 kDa
GenBank蛋白编号BC000725
基因名称 CD70
Gene ID (NCBI) 970
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP32970
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD70, also known as tumor necrosis factor ligand superfamily member 7 (TNFSF7) or CD27 ligand (CD27L), is a transmembrane protein that plays a significant role in the immune system. It is the unique ligand for CD27, a member of the tumor necrosis factor receptor (TNFR) family, and is transiently upregulated upon stimulation of immune cells. CD70 is expressed on lymphocytes and dendritic cells, and its expression can be regulated by activation signals received via toll-like receptors (TLRs), CD40, and the antigen receptor MHC II. It provides complex and not completely understood signaling for B cell development. CD70 is also expressed on various solid tumors and hematolymphoid malignancies, where it may contribute to a poor prognosis.

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