Anti-Human CD70 Rabbit Recombinant Antibody

CD70 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98098-1-RR

产品说明书

CloneNo. 241325D8

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

241325D8, CD27 L, CD27 ligand, CD27L, CD27-L

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


经过测试的应用

Positive FC detected inU266 cells

推荐稀释比

应用推荐稀释比
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

98098-1-RR targets CD70 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Recombinant Protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CD70 molecule
别名 241325D8, CD27 L, CD27 ligand, CD27L, CD27-L
计算分子量 21 kDa
GenBank蛋白编号BC000725
基因名称 CD70
Gene ID (NCBI) 970
RRIDAB_3672245
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP32970
储存缓冲液 PBS with 0.09% sodium azide , pH 7.3
储存条件Store at 2 - 8°C. Stable for one year after shipment.

背景介绍

CD70, also known as tumor necrosis factor ligand superfamily member 7 (TNFSF7) or CD27 ligand (CD27L), is a transmembrane protein that plays a significant role in the immune system. It is the unique ligand for CD27, a member of the tumor necrosis factor receptor (TNFR) family, and is transiently upregulated upon stimulation of immune cells. CD70 is expressed on lymphocytes and dendritic cells, and its expression can be regulated by activation signals received via toll-like receptors (TLRs), CD40, and the antigen receptor MHC II. It provides complex and not completely understood signaling for B cell development. CD70 is also expressed on various solid tumors and hematolymphoid malignancies, where it may contribute to a poor prognosis.

实验方案

Product Specific Protocols
FC protocol for CD70 antibody 98098-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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