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Host
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Species Reactivity
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Species Reactivity
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Compatible Species
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验证数据展示

  • FC experiment of human PBMCs using 98075-1-RR (same clone as 98075-1-PBS)

    FC experiment of human PBMCs using 98075-1-RR (same clone as 98075-1-PBS)

    1x10^6 human PBMCs were stained with CoraLite® Plus 647 Anti-Human CD19 (4G7) Mouse IgG2a Recombinant Antibody (CL647-65562, Clone: 4G7) and 0.25 ug Anti-Human CD79b Rabbit Recombinant Antibody (98075-1-RR, Clone:241273B7), or Isotype Control. Cells were not fixed. This data was developed using the same antibody clone with 98075-1-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 98075-1-RR (same clone as 98075-1-PBS)

    FC experiment of human PBMCs using 98075-1-RR (same clone as 98075-1-PBS)

    1x10^6 human PBMCs were stained with 0.25 ug Anti-Human CD79b Rabbit Recombinant Antibody (98075-1-RR, Clone:241273B7) (red), or Isotype Control(blue). Cells were not fixed. This data was developed using the same antibody clone with 98075-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98075-1-RR

    Affinity and Kinetic Characterization of 98075-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98075-1-RR against Human CD79b were performed. The affinity constant is 1.41 nM.

Anti-Human CD79b Rabbit Recombinant Antibody, PBS Only

CD79b Uni-rAbTM Recombinant Antibody for FC
Cat No. 98075-1-PBS

产品说明书

CloneNo. 241273B7

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

IGB, Ig beta, B-cell-specific glycoprotein B29, B-cell antigen receptor complex-associated protein beta chain, B29

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

98075-1-PBS targets CD79b in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Recombinant Protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CD79b molecule, immunoglobulin-associated beta
别名 IGB, Ig beta, B-cell-specific glycoprotein B29, B-cell antigen receptor complex-associated protein beta chain, B29
计算分子量 229 aa, 26 kDa
GenBank蛋白编号BC032651
基因名称 CD79B
Gene ID (NCBI) 974
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP40259
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD79 molecule encompasses two transmembrane proteins, CD79a and CD79b, which form a disulfide-linked heterodimer and are members of the immunoglobulin (Ig) gene superfamily (PMID: 2033258; 1375264; 2304550). CD79b molecule (also known as B29, IGB, AGM6, and Igbeta) is expressed almost exclusively on B cells and B-cell neoplasms, influencing antigen internalization and increasing antigen presentation efficiency (PMID: 7552998). CD79b mutation could be a key biomarker for DLBCL disease progression (PMID: 36182550).