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Anti-Human CD79b Rabbit Recombinant Antibody

CD79b Uni-rAbTM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

241273B7

Cat no : 98075-1-RR

Print datasheet

Synonyms

IGB, Ig beta, B-cell-specific glycoprotein B29, B-cell antigen receptor complex-associated protein beta chain, B29

验证数据展示

  • FC experiment of human PBMCs using 98075-1-RR

    FC experiment of human PBMCs using 98075-1-RR

    1x10^6 human PBMCs were stained with CoraLite® Plus 647 Anti-Human CD19 (4G7) Mouse IgG2a Recombinant Antibody (CL647-65562, Clone: 4G7) and 0.25 ug Anti-Human CD79b Rabbit Recombinant Antibody (98075-1-RR, Clone:241273B7), or Isotype Control. Cells were not fixed.

  • FC experiment of human PBMCs using 98075-1-RR

    FC experiment of human PBMCs using 98075-1-RR

    1x10^6 human PBMCs were stained with 0.25 ug Anti-Human CD79b Rabbit Recombinant Antibody (98075-1-RR, Clone:241273B7) (red), or Isotype Control(blue). Cells were not fixed.

  • Affinity and Kinetic Characterization of 98075-1-RR

    Affinity and Kinetic Characterization of 98075-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98075-1-RR against Human CD79b were performed. The affinity constant is 1.41 nM.

经过测试的应用

Positive FC detected inhuman PBMCs

推荐稀释比

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

98075-1-RR targets CD79b in FC applications and shows reactivity with human samples.

Tested Applications FC Application Description
Tested Reactivity human
Immunogen Recombinant Protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name CD79b molecule, immunoglobulin-associated beta
Synonyms IGB, Ig beta, B-cell-specific glycoprotein B29, B-cell antigen receptor complex-associated protein beta chain, B29
Calculated Molecular Weight 229 aa, 26 kDa
GenBank Accession NumberBC032651
Gene Symbol CD79B
Gene ID (NCBI) 974
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP40259
Storage Buffer PBS with 0.09% sodium azide, pH 7.3.
Storage ConditionsStore at 2 - 8°C. Stable for one year after shipment.

背景介绍

CD79 molecule encompasses two transmembrane proteins, CD79a and CD79b, which form a disulfide-linked heterodimer and are members of the immunoglobulin (Ig) gene superfamily (PMID: 2033258; 1375264; 2304550). CD79b molecule (also known as B29, IGB, AGM6, and Igbeta) is expressed almost exclusively on B cells and B-cell neoplasms, influencing antigen internalization and increasing antigen presentation efficiency (PMID: 7552998). CD79b mutation could be a key biomarker for DLBCL disease progression (PMID: 36182550).

实验方案

Product Specific Protocols
FC protocol for CD79b antibody 98075-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols