• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • FC experiment of human PBMCs using 65610-1-MR (same clone as 65610-1-PBS)

    FC experiment of human PBMCs using 65610-1-MR (same clone as 65610-1-PBS)

    1x10^6 human PBMCs were intracellularly stained with 0.25 ug Anti-Human CD79a (HM57) Mouse IgG2a RecAb (65610-1-MR, Clone:HM57) or Mouse IgG2a Isotype Control (C1.18.4) (65208-1-Ig, Clone: C1.18.4) and PE-conjugated Goat Anti-Mouse IgG2a. Cells were then stained with CoraLite® Plus 647 Anti-Human CD19. Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). Lymphocytes were gated. This data was developed using the same antibody clone with 65610-1-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 65610-1-MR (same clone as 65610-1-PBS)

    FC experiment of human PBMCs using 65610-1-MR (same clone as 65610-1-PBS)

    1x10^6 human PBMCs were intracellularly stained with 0.25 ug Anti-Human CD79a (HM57) Mouse IgG2a RecAb (65610-1-MR, Clone:HM57)(red) or Mouse IgG2a Isotype Control (C1.18.4) (65208-1-Ig, Clone: C1.18.4)(blue) and PE-conjugated Goat Anti-Mouse IgG2a. Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). Lymphocytes were gated. This data was developed using the same antibody clone with 65610-1-PBS in a different storage buffer formulation.

Anti-Human CD79a (HM57) Mouse IgG2a Recombinant Antibody, PBS Only

CD79a Uni-rAbTM Recombinant Antibody for FC (Intra)
Cat No. 65610-1-PBS

产品说明书

CloneNo. HM57

宿主/亚型

Mouse / IgG2a

种属反应性

human

应用

FC (Intra)

别名

MB-1 membrane glycoprotein, MB1, MB 1 membrane glycoprotein, MB 1, HM57

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

点击咨询售前客服

点击咨询售后客服

Planning an IHC experiment? We recommend our IHCeasy CD79a Ready-To-Use IHC Kit. CD79a primary antibody included.

产品信息

65610-1-PBS targets CD79a in FC (Intra) applications and shows reactivity with human samples.

经测试应用 FC (Intra) Application Description
经测试反应性 human
免疫原 Synthetic peptide corresponding to 202-216 amino acid sequence of human CD79a 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Recombinant
产品类型 Antibody
全称 CD79a molecule, immunoglobulin-associated alpha
别名 MB-1 membrane glycoprotein, MB1, MB 1 membrane glycoprotein, MB 1, HM57
GenBank蛋白编号BC113731
基因名称 CD79A
Gene ID (NCBI) 973
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD79a, also named as B-cell antigen receptor complex-associated protein alpha chain or MB-1 membrane glycoprotein, is a 226 amino acid protein, which contains one ITAM domain and one Ig-like C2-type (immunoglobulin-like) domain. CD79a is expressed in B cell and localizes in the cell membrane. CD79a is required in cooperation with CD79b for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79a is also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells.