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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • FC experiment of mouse splenocytes using 98025-1-RR (same clone as 98025-1-PBS)

    FC experiment of mouse splenocytes using 98025-1-RR (same clone as 98025-1-PBS)

    1x10^6 unstimulated or LPS stimulated mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD86 Rabbit Recombinant Antibody (98025-1-RR, Clone:230476B8) and PE-Conjugated Goat Anti-Rabbit IgG (H+L). Cells were not fixed. This data was developed using the same antibody clone with 98025-1-PBS in a different storage buffer formulation.

  • FC experiment of mouse splenocytes using 98025-1-RR (same clone as 98025-1-PBS)

    FC experiment of mouse splenocytes using 98025-1-RR (same clone as 98025-1-PBS)

    1x10^6 unstimulated (black) or LPS stimulated mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD86 Rabbit Recombinant Antibody (98025-1-RR, Clone:230476B8) and PE-Conjugated Goat Anti-Rabbit IgG (H+L) (red), or 0.25 ug Isotype Control (blue). Cells were not fixed. This data was developed using the same antibody clone with 98025-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98025-1-RR

    Affinity and Kinetic Characterization of 98025-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98025-1-RR against Mouse CD86 were performed. The affinity constant is 25.4 nM.

Anti-Mouse CD86 Rabbit Recombinant Antibody, PBS Only

CD86 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98025-1-PBS

产品说明书

CloneNo. 230476B8

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC

别名

B7-2, B70, B7.2, B7 2, B7

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

98025-1-PBS targets CD86 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原 Fusion Protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CD86 antigen
别名 B7-2, B70, B7.2, B7 2, B7
计算分子量35 kDa
GenBank蛋白编号NM_019388
基因名称 Cd86
Gene ID (NCBI) 12524
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP42082-1
储存缓冲液 PBS Only
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD86 (also known as B7-2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and CTLA-4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with CTLA-4 negatively regulates T-cell activation and diminishes the immune response. (PMID: 7513726; 1847722; 11029388; 27591335)