CD8b Monoclonal antibody, PBS Only

CD8b Monoclonal Antibody for IHC, Indirect ELISA
Cat No. 68432-1-PBS

产品说明书

CloneNo. 4B3B8

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

IHC, Indirect ELISA

CD8, 4B3B8, Ly3, Leu2, CD8B1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


产品信息

68432-1-PBS targets CD8b in IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 CD8b fusion protein Ag16925 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 CD8b molecule
别名 CD8, 4B3B8, Ly3, Leu2, CD8B1
计算分子量 243 aa, 27 kDa
GenBank蛋白编号BC100913
基因名称 CD8B
Gene ID (NCBI) 926
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP10966
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD8b (T-cell surface glycoprotein CD8 beta chain) is an integral membrane glycoprotein that forms disulfide-linked heterodimers with CD8a (CD8 alpha chain). The CD8 alpha/beta heterodimer is the predominant CD8 complex expressed on the cell surface (PMID: 1534146; 2111591). CD8 is a transmembrane glycoprotein predominantly expressed on cytotoxic T cells and can also be found on natural killer cells, cortical thymocytes, and dendritic cells. CD8 serves as a co-receptor for the T cell receptor (TCR). Both CD8 and TCR recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. CD8 plays a role in T cell development and activation of mature T cells.

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