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Anti-Human CD8b Rabbit Recombinant Antibody, PBS Only

CD8b Uni-rAbTM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

241326A7

Cat no : 98103-1-PBS

Print datasheet

Synonyms

CD8, 241326A7, Ly3, Leu2, CD8B1

验证数据展示

  • FC experiment of human PBMCs using 98103-1-RR (same clone as 98103-1-PBS)

    FC experiment of human PBMCs using 98103-1-RR (same clone as 98103-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD8b Rabbit Recombinant Antibody (98103-1-RR, Clone: 241326A7) or Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with APC Anti-Human CD3. Cells were not fixed. This data was developed using the same antibody clone with 98103-1-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 98103-1-RR (same clone as 98103-1-PBS)

    FC experiment of human PBMCs using 98103-1-RR (same clone as 98103-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD8b Rabbit Recombinant Antibody (98103-1-RR, Clone: 241326A7)(red), or Isotype Control (blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98103-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98103-1-RR

    Affinity and Kinetic Characterization of 98103-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98103-1-RR against Human CD8b were performed. The affinity constant is below 1 pM.

产品信息

98103-1-PBS targets CD8b in FC applications and shows reactivity with human samples.

Tested Applications FC Application Description
Tested Reactivity human
Immunogen Recombinant Protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name CD8b molecule
Synonyms CD8, 241326A7, Ly3, Leu2, CD8B1
Calculated Molecular Weight 243 aa, 27 kDa
GenBank Accession NumberBC100913
Gene Symbol CD8B
Gene ID (NCBI) 926
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP10966
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD8b (T-cell surface glycoprotein CD8 beta chain) is an integral membrane glycoprotein that forms disulfide-linked heterodimers with CD8a (CD8 alpha chain). The CD8 alpha/beta heterodimer is the predominant CD8 complex expressed on the cell surface (PMID: 1534146; 2111591). CD8 is a transmembrane glycoprotein predominantly expressed on the surface of cytotoxic T cells and can also be found on natural killer cells, cortical thymocytes, and dendritic cells. CD8 serves as a co-receptor for the T cell receptor (TCR). Both CD8 and TCR recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. CD8 plays a role in T cell development and activation of mature T cells.