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FcZero-rAb™ PE Anti-Mouse CD98/SLC3A2 Rabbit Recombinant Antibody

CD98/SLC3A2 FcZero-rAbTM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

FC

Conjugate

PE Fluorescent Dye

CloneNo.

241247F1

Cat no : PE-FcA98128

Print datasheet

Synonyms

Mdu1, CD98, Amino acid transporter heavy chain SLC3A2, 4F2hc, 4F2 cell-surface antigen heavy chain

验证数据展示

  • FC experiment of mouse splenocytes using PE-FcA98128

    FC experiment of mouse splenocytes using PE-FcA98128

    1x10^6 mouse splenocytes were surface stained with 0.25 ug PE Anti-Mouse CD98/SLC3A2 Rabbit Recombinant Antibody (PE-FcA98128, Clone: 241247F1), or 0.25 ug PE Rabbit IgG Isotype Control Recombinant Antibody (PE-FcA98136, Clone: 240953C9). Cells were not fixed.

  • FC experiment of mouse splenocytes using PE-FcA98128

    FC experiment of mouse splenocytes using PE-FcA98128

    1x10^6 mouse splenocytes were surface stained with 0.25 ug PE Anti-Mouse CD98/SLC3A2 Rabbit Recombinant Antibody (PE-FcA98128, Clone: 241247F1) (red), or 0.25 ug PE Rabbit IgG Isotype Control Recombinant Antibody (PE-FcA98136, Clone: 240953C9) (blue). Cells were not fixed.

经过测试的应用

Positive FC detected inmouse splenocytes

推荐稀释比

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

PE-FcA98128 targets CD98/SLC3A2 in FC applications and shows reactivity with mouse samples.

Tested Applications FC Application Description
Tested Reactivity mouse
Immunogen Recombinant protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
Synonyms Mdu1, CD98, Amino acid transporter heavy chain SLC3A2, 4F2hc, 4F2 cell-surface antigen heavy chain
Calculated Molecular Weight58 kDa
GenBank Accession NumberNM_008577.4
Gene Symbol CD98/SLC3A2
Gene ID (NCBI) 17254
Conjugate PE Fluorescent Dye
Excitation/Emission Maxima Wavelengths496 nm, 565 nm / 578 nm
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 0.09% sodium azide and 0.5% BSA.
Storage ConditionsStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

CD98 is a cell-surface heterodimer consisting of a heavy chain (CD98hc) and a light chain. CD98hc also interacts with certain integrin b-subunits to regulate cell migration, survival, proliferation, and adhesion/polarity. CD98hc is overexpressed on the cell surface of many cancers and increased CD98hc expression is associated with the development and progression of tumors.(PMID:25084765). This protein has 4 isoforms with the molecular mass of 58-71 kDa and can be detected 85-94 kDa due to glycosylation. The glycosylated CD98hc can links to a non-glycosylated light chain (~40 kDa) via a disulfide bond to form a heterodimeric CD98 antigen with molecular mass of 120-130 kDa (PMID: 14770309).

实验方案

Product Specific Protocols
FC protocol for PE CD98/SLC3A2 antibody PE-FcA98128Download protocol
Standard Protocols
Click here to view our Standard Protocols