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验证数据展示

  • WB analysis of HeLa using 12087-2-AP (same clone as 12087-2-PBS)

    WB analysis of HeLa using 12087-2-AP (same clone as 12087-2-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 12087-2-AP (CDA1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12087-2-PBS in a different storage buffer formulation.

  • IHC staining of human lung cancer using 12087-2-AP (same clone as 12087-2-PBS)

    IHC staining of human lung cancer using 12087-2-AP (same clone as 12087-2-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer using 12087-2-AP (CDA1 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 12087-2-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 12087-2-AP (same clone as 12087-2-PBS)

    IF Staining of HeLa using 12087-2-AP (same clone as 12087-2-PBS)

    Immunofluorescent analysis of Hela cells, using TSPYL2 antibody 12087-2-AP at 1:50 dilution and FITC-labeled donkey anti-rabbit IgG (green). Blue pseudocolor = DAPI (fluorescent DNA dye). This data was developed using the same antibody clone with 12087-2-PBS in a different storage buffer formulation.

  • IP experiment of HEK-293 using 12087-2-AP (same clone as 12087-2-PBS)

    IP experiment of HEK-293 using 12087-2-AP (same clone as 12087-2-PBS)

    IP result of anti-CDA1 (IP:12087-2-AP, 4ug; Detection:12087-2-AP 1:1000) with HEK-293 cells lysate 1000ug. This data was developed using the same antibody clone with 12087-2-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

CDA1 Polyclonal antibody, PBS Only

CDA1 Polyclonal Antibody for WB, IHC, IF/ICC, IP, Indirect ELISA
Cat No. 12087-2-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, IF/ICC, IP, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

12087-2-PBS targets CDA1 in WB, IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IF/ICC, IP, Indirect ELISA Application Description
经测试反应性 human
免疫原 CDA1 fusion protein Ag2722 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 TSPY-like 2
别名
计算分子量 693 aa, 79 kDa
观测分子量 120 kDa
GenBank蛋白编号BC024270
基因名称 CDA1
Gene ID (NCBI) 64061
RRIDAB_2256811
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H2G4
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TSPYL2 (also known as CINAP, CDA1, TSPX or DENTT) is a new member of the nucleosome assembly protein superfamily. TSPYL2 binds histones and facilitates nucleosome assembly. TSPYL2 is expressed in various tissues, highly in the pituitary gland and moderately in the adrenals, brain, testis, and ovary. Immunohistochemical staining analysis for TSPYL2 showed differential cytoplasmic and nuclear staining patterns in several cell types. Downregulated expression of TSPYL2 has been observed in several tumors, which suggests its role as a tumor suppressor. Although it is predicted that TSPYL2 has a molecular mass of 79.43 kDa, it is found that mammalian TSPYL2 appears at a size of 120 kDa by western blot analysis. The abundant acidic amino acid regions in TSPYL2 may cause its aberrant migration. In addition, the TSPYL2 protein is unstable and sensitive to proteasomal degradation.