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CES1 Monoclonal antibody, PBS Only

CES1 Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1C11C1

Cat no : 67079-1-PBS

Print datasheet

Synonyms

ACAT, Brain carboxylesterase hBr1, CEH, CES1, CES2, Cocaine carboxylesterase, Egasyn, HMSE, HMSE1, Liver carboxylesterase 1, PCE 1, REH, Retinyl ester hydrolase, Serine esterase 1, SES1, TGH, Triacylglycerol hydrolase

验证数据展示

  • WB analysis of U-937 using 67079-1-Ig (same clone as 67079-1-PBS)

    WB analysis of U-937 using 67079-1-Ig (same clone as 67079-1-PBS)

    U-937 cells were subjected to SDS PAGE followed by western blot with 67079-1-Ig (CES1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67079-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 67079-1-Ig (same clone as 67079-1-PBS)

    IHC staining of human liver using 67079-1-Ig (same clone as 67079-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 67079-1-Ig (CES1 antibody) at dilution of 1:600 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67079-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CES1 antibody included
  • IHC staining of human liver using 67079-1-Ig (same clone as 67079-1-PBS)

    IHC staining of human liver using 67079-1-Ig (same clone as 67079-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 67079-1-Ig (CES1 antibody) at dilution of 1:600 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67079-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CES1 antibody included
  • IF Staining of HepG2 using 67079-1-Ig (same clone as 67079-1-PBS)

    IF Staining of HepG2 using 67079-1-Ig (same clone as 67079-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using 67079-1-Ig (CES1 antibody) at dilution of 1:100 and CoraLite488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67079-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy CES1 Ready-To-Use IHC Kit. CES1 primary antibody included.

产品信息

67079-1-PBS targets CES1 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications WB, IHC, IF/ICC, Indirect ELISA Application Description
Tested Reactivity Human
Immunogen CES1 fusion protein Ag10647 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name carboxylesterase 1 (monocyte/macrophage serine esterase 1)
Synonyms ACAT, Brain carboxylesterase hBr1, CEH, CES1, CES2, Cocaine carboxylesterase, Egasyn, HMSE, HMSE1, Liver carboxylesterase 1, PCE 1, REH, Retinyl ester hydrolase, Serine esterase 1, SES1, TGH, Triacylglycerol hydrolase
Calculated Molecular Weight 566 aa, 62 kDa
Observed Molecular Weight 60-63 kDa
GenBank Accession NumberBC012418
Gene Symbol CES1
Gene ID (NCBI) 1066
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP23141
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CES1(liver carboxylesterase 1) is also named as CES2, SES1 and belongs to the type-B carboxylesterase/lipase family. The deduced 567-amino acid protein contains a putative 18-amino acid signal peptide and a characteristic C-terminal endoplasmic reticulum retention signal (HXEL). It is the major hydrolytic enzyme responsible for the metabolism of numerous therapeutic agents as well as endogenous substrates.Westernblot analysis demonstrated that CES1 is expressed in human liver microsomes (HLM) but not in human intestinal microsomes (HIM)(PMID:19185566).