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  • Featured Product
  • KD/KO Validated

CHRNA5 Monoclonal antibody, PBS Only

CHRNA5 Monoclonal Antibody for WB,Indirect ELISA,IHC

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse, pig

Applications

WB,Indirect ELISA,IHC

Conjugate

Unconjugated

CloneNo.

3G8C11

Cat No : 66363-1-PBS

Print datasheet

Synonyms

CHRNA5, LNCR2, NACHRA5

验证数据展示

  • WB analysis of mouse skeletal muscle using 66363-1-Ig (same clone as 66363-1-PBS)

    WB analysis of mouse skeletal muscle using 66363-1-Ig (same clone as 66363-1-PBS)

    mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 66363-1-Ig (CHRNA5 Antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66363-1-PBS in a different storage buffer formulation.

  • IHC staining of human bladder using 66363-1-Ig (same clone as 66363-1-PBS)

    IHC staining of human bladder using 66363-1-Ig (same clone as 66363-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human bladder tissue slide using 66363-1-Ig (CHRNA5 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 66363-1-PBS in a different storage buffer formulation.

  • IHC staining of human bladder using 66363-1-Ig (same clone as 66363-1-PBS)

    IHC staining of human bladder using 66363-1-Ig (same clone as 66363-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human bladder tissue slide using 66363-1-Ig (CHRNA5 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 66363-1-PBS in a different storage buffer formulation.

产品信息

66363-1-PBS targets CHRNA5 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, pig samples.

Tested Applications WB,Indirect ELISA,IHC Application Description
Tested Reactivity human, mouse, pig
Immunogen CHRNA5 fusion protein Ag4447 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name cholinergic receptor, nicotinic, alpha 5
Synonyms CHRNA5, LNCR2, NACHRA5
Calculated Molecular Weight 468 aa, 53 kDa
Observed Molecular Weight 53 kDa
GenBank Accession NumberBC033639
Gene Symbol CHRNA5
Gene ID (NCBI) 1138
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP30532
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

Nicotinic acetylcholine receptors (nAChRs), such as CHRNA5, are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be (hetero)pentamers composed of homologous subunits. Variants in the CHRNA5 gene are associated with nicotine dependence and lung cancer risk.