验证数据展示
产品信息
66363-1-PBS targets CHRNA5 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, pig samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | human, mouse, pig |
免疫原 | CHRNA5 fusion protein Ag4447 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | cholinergic receptor, nicotinic, alpha 5 |
别名 | CHRNA5, LNCR2, NACHRA5 |
计算分子量 | 468 aa, 53 kDa |
观测分子量 | 53 kDa |
GenBank蛋白编号 | BC033639 |
基因名称 | CHRNA5 |
Gene ID (NCBI) | 1138 |
RRID | AB_2881743 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P30532 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Nicotinic acetylcholine receptors (nAChRs), such as CHRNA5, are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be (hetero)pentamers composed of homologous subunits. Variants in the CHRNA5 gene are associated with nicotine dependence and lung cancer risk.