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CLEC10A/CD301 Polyclonal antibody

CLEC10A/CD301 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 13590-1-AP

Print datasheet

Synonyms

CLEC10A, CD301, C-type lectin superfamily member 14, C-type lectin domain family 10 member A, CLECSF14

验证数据展示

  • WB analysis of BxPC-3 using 13590-1-AP

    WB analysis of BxPC-3 using 13590-1-AP

    BxPC-3 cells were subjected to SDS PAGE followed by western blot with 13590-1-AP (CLEC10A/CD301 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inBxPC-3 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

13590-1-AP targets CLEC10A/CD301 in WB, ELISA applications and shows reactivity with human samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human
Immunogen CLEC10A/CD301 fusion protein Ag4490 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name C-type lectin domain family 10, member A
Synonyms CLEC10A, CD301, C-type lectin superfamily member 14, C-type lectin domain family 10 member A, CLECSF14
Calculated Molecular Weight 316 aa, 35 kDa
Observed Molecular Weight 32 kDa, 28 kDa
GenBank Accession NumberBC039011
Gene Symbol CLEC10A
Gene ID (NCBI) 10462
RRIDAB_2083131
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8IUN9
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

C-type lectin domain family 10 member A (CLEC10A), also known as CD301, macrophage galactose-type C-type lectin (MGL), DC-asialoglyco protein receptor (DC-ASGP-R) or human macrophage lectin (HML), is a type II transmembrane glycoprotein having a calcium-dependent carbohydrate recognition domain (PMID: 8598452; 11919201; 11698450). CLEC10A is expressed exclusively by myeloid professional antigen-presenting cells such as immature dendritic cells (DCs) and alternatively activated macrophages (PMID: 16998493). CLEC10A is a marker for human CD1c+ DCs (cDC2) (PMID: 29755453). It functions as an endocytic receptor for glycosylated antigens (PMID: 11919201).

实验方案

Product Specific Protocols
WB protocol for CLEC10A/CD301 antibody 13590-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols