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CLUL1 Polyclonal antibody

CLUL1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 27498-1-AP

Print datasheet

Synonyms

Retinal-specific clusterin-like protein, Clusterin-like protein 1, Clusterin like protein 1, clusterin like 1 (retinal)

验证数据展示

  • WB analysis using 27498-1-AP

    WB analysis using 27498-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 27498-1-AP (CLUL1 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inARPE-19 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

27498-1-AP targets CLUL1 in WB, ELISA applications and shows reactivity with human samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human
Immunogen CLUL1 fusion protein Ag26570 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name clusterin-like 1 (retinal)
Synonyms Retinal-specific clusterin-like protein, Clusterin-like protein 1, Clusterin like protein 1, clusterin like 1 (retinal)
Calculated Molecular Weight 54 kDa
Observed Molecular Weight70 kDa
GenBank Accession NumberBC025381
Gene Symbol CLUL1
Gene ID (NCBI) 27098
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ15846
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Clusterin-like protein 1 (CLUL1) functions as a molecular chaperone, protecting stressed proteins, and is upregulated in various neurodegenerative conditions, suggesting a role in defense against neuronal damage (PMID: 17148042). It is specifically expressed in cone photoreceptor cells and is regulated by the cone-rod homeobox (CRX) (PMID: 14507903). Mutations of CLUL1 were investigated in the context of age-related macular degeneration (AMD), a leading cause of blindness in the elderly (PMID: 17148042).

实验方案

Product Specific Protocols
WB protocol for CLUL1 antibody 27498-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols