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验证数据展示

  • WB analysis using 30025-1-AP

    WB analysis using 30025-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 30025-1-AP (CNDP2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

CNDP2 Polyclonal antibody

CNDP2 Polyclonal Antibody for WB, ELISA
Cat No. 30025-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

Human

应用

WB, ELISA

别名

CN2, CNDP dipeptidase 2, CNDP2, CPGL, FLJ10830, HsT2298, PEPA, Peptidase A

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive WB detected inHEK-293T cells, HL-60 cells, Jurkat cells, PC-3 cells, U-251 cells, U-937 cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:2000-1:10000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

30025-1-AP targets CNDP2 in WB, ELISA applications and shows reactivity with Human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 Human
免疫原 CNDP2 fusion protein Ag32312 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 CNDP dipeptidase 2 (metallopeptidase M20 family)
别名 CN2, CNDP dipeptidase 2, CNDP2, CPGL, FLJ10830, HsT2298, PEPA, Peptidase A
计算分子量 53 kDa
观测分子量 44-53 kDa
GenBank蛋白编号BC001375
基因名称 CNDP2
Gene ID (NCBI) 55748
RRIDAB_2935503
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ96KP4
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Carnosine dipeptidase II (CNDP2) catalyzes the peptide bond hydrolysis in dipeptides, displaying a non-redundant activity toward threonyl dipeptides. It has high dipeptidase activity toward cysteinyl glycine, an intermediate metabolite in glutathione metabolism (PubMed:19346245, PubMed:12473676). Metabolizes N-lactoyl-amino acids, both through hydrolysis to form lactic acid and amino acids, as well as through their formation by reverse proteolysis (PubMed:25964343). CNDP2 has 2 isoforms with a molecular weight of 53 and 44 kDa. The isoform 1 is ubiquitously expressed with higher levels in the kidney and liver (at protein level) and expressed in peripheral blood leukocytes (PubMed:12473676). It is also expressed in gastric mucosa and down-regulated in gastric cancer mucosal tissues (at the protein level) (PubMed:24395568). Isoform 2 is broadly expressed in fetal tissues and expressed in the adult liver and placenta. (PMID: 17121880).

实验方案

Product Specific Protocols
WB protocol for CNDP2 antibody 30025-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols