COMMD5 Monoclonal antibody

COMMD5 Monoclonal Antibody for WB, ELISA
Cat No. 67043-1-Ig

产品说明书

CloneNo. 1E10G6

宿主/亚型

Mouse / IgG2a

种属反应性

Human, Rat and More (1)

应用

WB, ELISA

COMM domain containing 5, COMMD5, FLJ13008, HCARG, HT002

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inhuman heart tissue, rat heart tissue, MCF-7 cells, HEK-293 cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:2000-1:6000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

WBSee 2 publications below

产品信息

67043-1-Ig targets COMMD5 in WB, ELISA applications and shows reactivity with Human, Rat samples.

经测试应用 WB, ELISA Application Description
文献引用应用WB
经测试反应性 Human, Rat
文献引用反应性human
免疫原 COMMD5 fusion protein Ag18464 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 COMM domain containing 5
别名 COMM domain containing 5, COMMD5, FLJ13008, HCARG, HT002
计算分子量 25 kDa
观测分子量 15 kDa
GenBank蛋白编号BC003055
基因名称 COMMD5
Gene ID (NCBI) 28991
RRIDAB_2882357
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ9GZQ3
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Aliquoting is unnecessary for -20oC storage.

背景介绍

COMM domain containing 5 (COMMD5, synonyms: HCARG, HT002) is a hypertension-related calcium-regulated gene. COMMD5 is negatively regulated by extracellular calcium concentration, and its basal mRNA levels were higher in hypertensive animals. Tissue distribution of COMMD5 shows a preponderance in the heart, stomach, jejunum, kidney (tubular fraction), liver, and adrenal gland (mainly in the medulla). COMMD5 mRNA is significantly more expressed in adult than in fetal organs, and its levels are decreased in tumors and cancerous cell lines. COMMD5 protein has no transmembrane domain, but contains 67% -helix content, a calcium-binding site, four putative "leucine zipper" motifs, and a nuclear receptor-binding domain. At the subcellular level, COMMD5 shows a nuclear localization.

实验方案

Product Specific Protocols
WB protocol for COMMD5 antibody 67043-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Cell

Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome

Authors - Michael D Healy
humanWB

Aging (Albany NY)

TMT-based quantitative proteomic analysis revealed that FBLN2 and NPR3 are involved in the early osteogenic differentiation of mesenchymal stem cells (MSCs)

Authors - Jianyun Liu
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