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验证数据展示

  • WB analysis of human heart using 67043-1-Ig (same clone as 67043-1-PBS)

    WB analysis of human heart using 67043-1-Ig (same clone as 67043-1-PBS)

    human heart tissue were subjected to SDS PAGE followed by western blot with 67043-1-Ig (COMMD5 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67043-1-PBS in a different storage buffer formulation.

COMMD5 Monoclonal antibody, PBS Only

COMMD5 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 67043-1-PBS

产品说明书

CloneNo. 1E10G6

宿主/亚型

Mouse / IgG2a

种属反应性

Human, Rat

应用

WB, Indirect ELISA

别名

COMM domain containing 5, COMMD5, FLJ13008, HCARG, HT002

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67043-1-PBS targets COMMD5 in WB, Indirect ELISA applications and shows reactivity with Human, Rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human, Rat
免疫原 COMMD5 fusion protein Ag18464 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 COMM domain containing 5
别名 COMM domain containing 5, COMMD5, FLJ13008, HCARG, HT002
计算分子量 25 kDa
观测分子量 15 kDa
GenBank蛋白编号BC003055
基因名称 COMMD5
Gene ID (NCBI) 28991
RRIDAB_2882357
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ9GZQ3
储存缓冲液 PBS Only
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

COMM domain containing 5 (COMMD5, synonyms: HCARG, HT002) is a hypertension-related calcium-regulated gene. COMMD5 is negatively regulated by extracellular calcium concentration, and its basal mRNA levels were higher in hypertensive animals. Tissue distribution of COMMD5 shows a preponderance in the heart, stomach, jejunum, kidney (tubular fraction), liver, and adrenal gland (mainly in the medulla). COMMD5 mRNA is significantly more expressed in adult than in fetal organs, and its levels are decreased in tumors and cancerous cell lines. COMMD5 protein has no transmembrane domain, but contains 67% -helix content, a calcium-binding site, four putative "leucine zipper" motifs, and a nuclear receptor-binding domain. At the subcellular level, COMMD5 shows a nuclear localization.