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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis of pig cartilage using 66793-1-Ig (same clone as 66793-1-PBS)

    WB analysis of pig cartilage using 66793-1-Ig (same clone as 66793-1-PBS)

    pig cartilage tissue were subjected to SDS PAGE followed by western blot with 66793-1-Ig (COMP antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66793-1-PBS in a different storage buffer formulation.

  • IF Staining of HepG2 using 66793-1-Ig (same clone as 66793-1-PBS)

    IF Staining of HepG2 using 66793-1-Ig (same clone as 66793-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using COMP antibody (66793-1-Ig, Clone: 1D7A6 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L), CL594-Phalloidin (red). This data was developed using the same antibody clone with 66793-1-PBS in a different storage buffer formulation.

  • IF Staining of U2OS using 66793-1-Ig (same clone as 66793-1-PBS)

    IF Staining of U2OS using 66793-1-Ig (same clone as 66793-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed U2OS cells using COMP antibody (66793-1-Ig, Clone: 1D7A6 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66793-1-PBS in a different storage buffer formulation.

COMP Monoclonal antibody, PBS Only

COMP Monoclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 66793-1-PBS

产品说明书

CloneNo. 1D7A6

宿主/亚型

Mouse / IgG1

种属反应性

Human, pig

应用

WB, IF/ICC, Indirect ELISA

别名

COMP, EDM1, EPD1, MED, PSACH, THBS5, Thrombospondin 5, TSP5

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

66793-1-PBS targets COMP in WB, IF/ICC, Indirect ELISA applications and shows reactivity with Human, pig samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 Human, pig
免疫原 COMP fusion protein Ag4575 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 cartilage oligomeric matrix protein
别名 COMP, EDM1, EPD1, MED, PSACH, THBS5, Thrombospondin 5, TSP5
计算分子量 757 aa, 83 kDa
观测分子量 100-130 kDa
GenBank蛋白编号BC033676
基因名称 COMP
Gene ID (NCBI) 1311
RRIDAB_2882137
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP49747
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

COMP is a secreted pentameric glycoprotein built from modular units and belongs to the thrombospondin protein family. COMP is expressed by hypertrophic chondrocytes and osteoblasts during endochondral ossification, and its expression is increased during fracture healing. COMP is involved in the assembly of collagen fibrils and other structural matrix components. COMP interacts with a number of cartilage ECM proteins, including fibronectin, collagen I, II IX, XII, and XIV, matrilins, as well as proteoglycans such as aggrecan and others. This antibody got 100-130 kDa maybe due to glycosylation.