• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis of mouse brain using 20249-1-AP (same clone as 20249-1-PBS)

    WB analysis of mouse brain using 20249-1-AP (same clone as 20249-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 20249-1-AP (CPLX2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20249-1-PBS in a different storage buffer formulation.

  • IHC staining of human brain using 20249-1-AP (same clone as 20249-1-PBS)

    IHC staining of human brain using 20249-1-AP (same clone as 20249-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain slide using 20249-1-AP (CPLX2 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 20249-1-PBS in a different storage buffer formulation.

CPLX2 Polyclonal antibody, PBS Only

CPLX2 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 20249-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

点击咨询售前客服

点击咨询售后客服

产品信息

20249-1-PBS targets CPLX2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 complexin 2
别名
计算分子量 15 kDa
观测分子量 20 kDa
GenBank蛋白编号NM_006650
基因名称 CPLX2
Gene ID (NCBI) 10814
RRIDAB_11232598
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ6PUV4
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Complexins are soluble proteins that regulate the activity of soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complexes necessary for vesicle fusion. Neuronal specific complexin 1 (CPLX1) has inhibitory and stimulatory effects on exocytosis by clamping trans-SNARE complexes in a prefusion state and promoting conformational changes to facilitate membrane fusion following cell stimulation. Complexin2 (CPLX2) is a pre-synaptic protein believed to regulate neurotransmitter release from pre-synaptic terminals, it is downregulated in schizophrenic patients suffering from depression, animal models of depression and neurological disorders such as Huntington's disease in which depression is a major symptom. This antibody is expected to specifically recogize CPLX2 but not other complexins.