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CREB3 Monoclonal antibody, PBS Only

CREB3 Monoclonal Antibody for WB,Indirect ELISA,IF

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB,Indirect ELISA,IF

Conjugate

Unconjugated

CloneNo.

1C12H11

Cat No : 68379-1-PBS

Print datasheet

Synonyms

CREB 3, CREB3, LUMAN, LZIP

验证数据展示

  • WB analysis of HCT 116 using 68379-1-Ig (same clone as 68379-1-PBS)

    WB analysis of HCT 116 using 68379-1-Ig (same clone as 68379-1-PBS)

    HCT 116 cells were subjected to SDS PAGE followed by western blot with 68379-1-Ig (CREB3 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68379-1-PBS in a different storage buffer formulation.

  • WB analysis using 68379-1-Ig (same clone as 68379-1-PBS)

    WB analysis using 68379-1-Ig (same clone as 68379-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68379-1-Ig (CREB3 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68379-1-PBS in a different storage buffer formulation.

  • IF Staining of U2OS using 68379-1-Ig (same clone as 68379-1-PBS)

    IF Staining of U2OS using 68379-1-Ig (same clone as 68379-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed U2OS cells using CREB3 antibody (68379-1-Ig, Clone: 1C12H11 ) at dilution of 1:800 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 68379-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy CREB3 Ready-To-Use IHC Kit. CREB3 primary antibody included.

产品信息

68379-1-PBS targets CREB3 in WB, IF, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications WB,Indirect ELISA,IF Application Description
Tested Reactivity Human
Immunogen CREB3 fusion protein Ag1823 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name cAMP responsive element binding protein 3
Synonyms CREB 3, CREB3, LUMAN, LZIP
Calculated Molecular Weight 44 kDa
Observed Molecular Weight 40-64 kDa
GenBank Accession NumberBC009402
Gene Symbol CREB3
Gene ID (NCBI) 10488
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDO43889
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

CREB3, also named as LZIP and Luman, belongs to the bZIP family and ATF subfamily. It is a transcription factors activated upon intramembrane proteolysis (RIP), binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. CREB3 binds to and requires HCFC1 as a coactivator. The activity and expression are suppressed when the HCFC1-CREB3 complex binds with CREBZF. Participates in LKN-1/CCL15-induced chemotaxis signaling. CREB3 is N-glycosylated and released by proteolysis. So the MW of CREB3 emirate 40kd to 64kd (PMID: 12138176).