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验证数据展示

  • WB analysis of HEK-293 using 67035-1-Ig (same clone as 67035-1-PBS)

    WB analysis of HEK-293 using 67035-1-Ig (same clone as 67035-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 67035-1-Ig (CRK antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67035-1-PBS in a different storage buffer formulation.

CRK Monoclonal antibody, PBS Only

CRK Monoclonal Antibody for WB, ELISA
Cat No. 67035-1-PBS

产品说明书

CloneNo. 2B7E1

宿主/亚型

Mouse / IgG1

种属反应性

Human, mouse, rat

应用

WB, ELISA

别名

Adapter molecule crk, CRK, CRKII, p38, Proto oncogene c Crk

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67035-1-PBS targets CRK in WB, ELISA applications and shows reactivity with Human, mouse, rat samples.

经测试应用 WB, ELISA Application Description
经测试反应性 Human, mouse, rat
免疫原 CRK fusion protein Ag28793 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 v-crk sarcoma virus CT10 oncogene homolog (avian)
别名 Adapter molecule crk, CRK, CRKII, p38, Proto oncogene c Crk
计算分子量 34 kDa
观测分子量 34 kDa
GenBank蛋白编号BC008506
基因名称 CRK
Gene ID (NCBI) 1398
RRIDAB_2882350
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP46108
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CRK is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. CRK has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation.