CRK Monoclonal antibody

CRK Monoclonal Antibody for WB, ELISA
Cat No. 67035-1-Ig

产品说明书

CloneNo. 2B7E1

宿主/亚型

Mouse / IgG1

种属反应性

Human, mouse, rat

应用

WB, ELISA

Adapter molecule crk, CRK, CRKII, p38, Proto oncogene c Crk

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
Biotin
规格: 

-/ -


经过测试的应用

Positive WB detected inHEK-293 cells, HeLa cells, HSC-T6 cells, Jurkat cells, NIH/3T3 cells, RAW 264.7 cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:6000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

67035-1-Ig targets CRK in WB, ELISA applications and shows reactivity with Human, mouse, rat samples.

经测试应用 WB, ELISA Application Description
经测试反应性 Human, mouse, rat
免疫原 CRK fusion protein Ag28793 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 v-crk sarcoma virus CT10 oncogene homolog (avian)
别名 Adapter molecule crk, CRK, CRKII, p38, Proto oncogene c Crk
计算分子量 34 kDa
观测分子量 34 kDa
GenBank蛋白编号BC008506
基因名称 CRK
Gene ID (NCBI) 1398
RRIDAB_2882350
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP46108
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Aliquoting is unnecessary for -20oC storage.

背景介绍

CRK is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. CRK has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation.

实验方案

Product Specific Protocols
WB protocol for CRK antibody 67035-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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