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CRX Monoclonal antibody, PBS Only

CRX Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse, rat, pig

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1C3C11

Cat no : 67555-1-PBS

Print datasheet

Synonyms

cone rod homeobox, Cone rod homeobox protein, CORD2, CRD, CRX, LCA7, OTX3

验证数据展示

  • WB analysis using 67555-1-Ig (same clone as 67555-1-PBS)

    WB analysis using 67555-1-Ig (same clone as 67555-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67555-1-Ig (CRX antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67555-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse eye using 67555-1-Ig (same clone as 67555-1-PBS)

    IHC staining of mouse eye using 67555-1-Ig (same clone as 67555-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse eye tissue slide using 67555-1-Ig (CRX antibody) at dilution of 1:4000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67555-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CRX antibody included
Planning an IHC experiment? We recommend our IHCeasy CRX Ready-To-Use IHC Kit. CRX primary antibody included.

产品信息

67555-1-PBS targets CRX in WB, IHC, Indirect ELISA applications and shows reactivity with Human, mouse, rat, pig samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity Human, mouse, rat, pig
Immunogen CRX fusion protein Ag30086 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name cone-rod homeobox
Synonyms cone rod homeobox, Cone rod homeobox protein, CORD2, CRD, CRX, LCA7, OTX3
Calculated Molecular Weight 299 aa, 32 kDa
Observed Molecular Weight 37 kDa
GenBank Accession NumberBC016664
Gene Symbol CRX
Gene ID (NCBI) 1406
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDO43186
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Cone-rod homeobox (Crx) is a homeodomain transcription factor and member of the Otx family, which has been thought to play a critical role in determining and maintaining the phenotype of both pinealocytes and retinal photoreceptors [PMID:17467693]. In the mammalian retina, Crx plays an essential role in the normal development and maintenance of cones and rods and regulates expression of the network of genes that characterize the retina [PMID:17653270]. Elimination of Crx by disruption of the homeobox domain results in loss of the image-forming visual system but not the non-image-forming visual system controlling circadian rhythms [PMID:20438719].