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CSDC2 Recombinant antibody

CSDC2 Uni-rAbTM Recombinant Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

241031C8

Cat no : 83886-5-RR

Print datasheet

Synonyms

RNA-binding protein PIPPin, RNA binding protein PIPPin, PIPPIN, Cold shock domain-containing protein C2, 241031C8

验证数据展示

  • WB analysis using 83886-5-RR

    WB analysis using 83886-5-RR

    Various lysates were subjected to SDS PAGE followed by western blot with 83886-5-RR (CSDC2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

  • Affinity and Kinetic Characterization of 83886-5-RR

    Affinity and Kinetic Characterization of 83886-5-RR

    Biolayer interferometry (BLl) kinetic assays of 83886-5-RR against Human CSDC2 were performed. The affinity constant is 1.49 nM.

经过测试的应用

Positive WB detected inHeLa cells, U2OS cells, U-251 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:2000-1:10000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

The immunogen of 83886-5-RR is CSDC2 Fusion Protein expressed in E. coli.

Tested Applications WB, ELISA Application Description
Tested Reactivity human
Immunogen CSDC2 fusion protein Ag16216 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name cold shock domain containing C2, RNA binding
Synonyms RNA-binding protein PIPPin, RNA binding protein PIPPin, PIPPIN, Cold shock domain-containing protein C2, 241031C8
Calculated Molecular Weight 153 aa, 17 kDa
Observed Molecular Weight20 kDa, 30 kDa
GenBank Accession NumberBC067113
Gene Symbol CSDC2
Gene ID (NCBI) 27254
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ9Y534
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

PIPPIN, also known as CSDC2 (Cold shock domain-containing protein C2) is an RNA‐binding protein (RBP), highly enriched in the rat brain, specifically enriched in some pyramidal neurons of the cerebral cortex and in the Purkinje cells of the cerebellum (PMID: 10446180). PIPPIN has the potential to undergo different posttranslational modifications and might be a good candidate to regulate the synthesis of specific proteins in response to extracellular stimuli. Nuclear CSDC2 is connected to proliferation and cytoplasmic CSDC2 to terminal differentiation in the decidua and that CSDC2 could regulate differentiation during decidua development (PMID: 30078185, PMID: 17053029).

实验方案

Product Specific Protocols
WB protocol for CSDC2 antibody 83886-5-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols