• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 13319-1-AP (same clone as 13319-1-PBS)

    WB analysis using 13319-1-AP (same clone as 13319-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 13319-1-AP (CSDE1 antibody) at dilution of 1:7000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13319-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 13319-1-AP (same clone as 13319-1-PBS)

    IHC staining of human liver cancer using 13319-1-AP (same clone as 13319-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 13319-1-AP (CSDE1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13319-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CSDE1 antibody included
  • IF Staining of HeLa using 13319-1-AP (same clone as 13319-1-PBS)

    IF Staining of HeLa using 13319-1-AP (same clone as 13319-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using CSDE1 antibody (13319-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-Phalloidin (red). This data was developed using the same antibody clone with 13319-1-PBS in a different storage buffer formulation.

  • WB analysis of A431 using 13319-1-AP (same clone as 13319-1-PBS)

    WB analysis of A431 using 13319-1-AP (same clone as 13319-1-PBS)

    WB result of CSDE1 antibody (13319-1-AP; 1:20000; incubated at room temperature for 1.5 hours) with sh-Control and sh-CSDE1 transfected A431 cells. This data was developed using the same antibody clone with 13319-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

CSDE1 Polyclonal antibody, PBS Only

CSDE1 Polyclonal Antibody for WB, IHC, IF/ICC, ELISA
Cat No. 13319-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, IF/ICC, ELISA

别名

UNR, NRU, N-ras upstream gene protein, KIAA0885, Cold shock domain-containing protein E1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

点击咨询售前客服

点击咨询售后客服

Planning an IHC experiment? We recommend our IHCeasy CSDE1 Ready-To-Use IHC Kit. CSDE1 primary antibody included.

产品信息

13319-1-PBS targets CSDE1 in WB, IHC, IF/ICC, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, IF/ICC, ELISA Application Description
经测试反应性 human, mouse
免疫原 CSDE1 fusion protein Ag4173 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 cold shock domain containing E1, RNA-binding
别名 UNR, NRU, N-ras upstream gene protein, KIAA0885, Cold shock domain-containing protein E1
计算分子量 798 aa, 89 kDa
观测分子量 89 kDa
GenBank蛋白编号BC032446
基因名称 CSDE1
Gene ID (NCBI) 7812
RRIDAB_2084902
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO75534
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CSDE1 (Cold shock domain-containing protein E1), also known as UNR (upstream of N-ras), is an RNA-binding protein involved in the regulation of messenger RNA stability and internal initiation of translation. It is required for internal initiation of translation of human rhinovirus RNA. UNR may be involved in translationally coupled mRNA turnover. Reduced expression of UNR impairs proliferation and differentiation of erythroid blasts. Recent study found that UNR acts as a positive or negative regulator of cell death, depending on the cell type, suggesting manipulation of UNR level may constitute a specific approach to sensitize cancer cells to anticancer treatments.