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CSNK1A1 Polyclonal antibody

CSNK1A1 Polyclonal Antibody for WB, IHC, IF/ICC, ELISA
Cat No. 55192-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, ELISA and More (3)

CSNK1, CSNK, CKI-alpha, CKI alpha, CK1α

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inHeLa cells
Positive IHC detected inhuman breast cancer tissue, human lung cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF/ICC detected inA549 cells
Planning an IHC experiment? We recommend our IHCeasy CSNK1A1 Ready-To-Use IHC Kit. CSNK1A1 primary antibody included.

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:4000
Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)/ICCIF/ICC : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

55192-1-AP targets CSNK1A1 in WB, IHC, IF/ICC, IP, CoIP, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, ELISA Application Description
文献引用应用WB, IHC, IF, IP, CoIP
经测试反应性 human, mouse, rat
文献引用反应性human, mouse
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 casein kinase 1, alpha 1
别名 CSNK1, CSNK, CKI-alpha, CKI alpha, CK1α
计算分子量 42 kDa
观测分子量30-35 kDa, 42-45 kDa
GenBank蛋白编号NM_001892
基因名称 CSNK1A1
Gene ID (NCBI) 1452
RRIDAB_11183034
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP48729
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

CSNK1A1, also named as CK1, belongs to the protein kinase superfamily, CK1 Ser/Thr protein kinase family and Casein kinase I subfamily. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. CSNK1A1 can phosphorylate a large number of proteins. It participates in Wnt signaling. CSNK1A1 phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis. This antibody is specific to CSNK1A1.

实验方案

Product Specific Protocols
WB protocol for CSNK1A1 antibody 55192-1-APDownload protocol
IHC protocol for CSNK1A1 antibody 55192-1-APDownload protocol
IF protocol for CSNK1A1 antibody 55192-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB,IHC

Pharmacol Res

Upregulation of CSNK1A1 induced by ITGB5 confers to hepatocellular carcinoma resistance to sorafenib in vivo by disrupting the EPS15/EGFR complex

Authors - Li Gu
  • KD Validated
WB

J Cell Biol

CHMP2B regulates TDP-43 phosphorylation and cytotoxicity independent of autophagy via CK1.

Authors - Xue Deng
humanIP

Virol Sin

CK1α upregulates the IFNAR1 expression to prompt the anti-HBV effect of type I IFN in hepatoma carcinoma cells

Authors - Jing Xiong
mouseWB,IF

Stem Cell Res Ther

Nicotinamide improves in vitro lens regeneration in a mouse capsular bag model.

Authors - Xiaomin Liu
humanWB

Int J Biol Sci

Pantothenate Kinase 1 Inhibits the Progression of Hepatocellular Carcinoma by Negatively Regulating Wnt/β-catenin Signaling.

Authors - Yuyuan Zi
mouseWB,IF

Endocrinology

Casein kinase 1α regulates testosterone synthesis and testis development in adult mice

Authors - Hongzhou Guo
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