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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 20123-1-AP (same clone as 20123-1-PBS)

    WB analysis using 20123-1-AP (same clone as 20123-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 20123-1-AP (CUEDC2 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20123-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse brain using 20123-1-AP (same clone as 20123-1-PBS)

    IP experiment of mouse brain using 20123-1-AP (same clone as 20123-1-PBS)

    IP result of anti-CUEDC2 (IP:20123-1-AP, 4ug; Detection:20123-1-AP 1:500) with mouse brain tissue lysate 4000ug. This data was developed using the same antibody clone with 20123-1-PBS in a different storage buffer formulation.

  • IHC staining of human ovary tumor using 20123-1-AP (same clone as 20123-1-PBS)

    IHC staining of human ovary tumor using 20123-1-AP (same clone as 20123-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 20123-1-AP (CUEDC2 antibody) at dilution of 1:800 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20123-1-PBS in a different storage buffer formulation.

  • IHC staining of human ovary tumor using 20123-1-AP (same clone as 20123-1-PBS)

    IHC staining of human ovary tumor using 20123-1-AP (same clone as 20123-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 20123-1-AP (CUEDC2 antibody) at dilution of 1:800 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20123-1-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 20123-1-AP (same clone as 20123-1-PBS)

    IF Staining of HeLa using 20123-1-AP (same clone as 20123-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed HeLa cells using CUEDC2 antibody (20123-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 20123-1-PBS in a different storage buffer formulation.

CUEDC2 Polyclonal antibody, PBS Only

CUEDC2 Polyclonal Antibody for WB, IHC, IF/ICC, IP, Indirect ELISA
Cat No. 20123-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, IF/ICC, IP, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

20123-1-PBS targets CUEDC2 in WB, IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, IF/ICC, IP, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 CUEDC2 fusion protein Ag13847 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 CUE domain containing 2
别名
计算分子量 287 aa, 32 kDa
观测分子量 32 kDa
GenBank蛋白编号BC000262
基因名称 CUEDC2
Gene ID (NCBI) 79004
RRIDAB_10638318
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H467
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CUE domain-containing 2 (CUEDC2) is a ubiquitin-binding motif-containing protein involved in the regulation of the cell cycle, inflammation, and tumorigenesis. It is ubiquitously expressed in human tissues and organs, not only highly expressed in the normal brain, heart and testis, but also some kinds of cancers, such as breast, ovarian and kidney cancers. CUEDC2 could act as an adaptor protein to target IκB kinase (IKK) for dephosphorylation and inactivation by recruiting protein phosphatase (PP1), and thus repressed activation of the transcription factor NF-κB. Moreover, CUEDC2, is a key factor in endocrine resistance in breast cancer.