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CUL2 Polyclonal antibody, PBS Only

CUL2 Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 30071-1-PBS

Print datasheet

Synonyms

验证数据展示

  • WB analysis using 30071-1-AP (same clone as 30071-1-PBS)

    WB analysis using 30071-1-AP (same clone as 30071-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30071-1-AP (CUL2 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30071-1-PBS in a different storage buffer formulation.

  • WB analysis of PC-3 using 30071-1-AP (same clone as 30071-1-PBS)

    WB analysis of PC-3 using 30071-1-AP (same clone as 30071-1-PBS)

    WB result of CUL2 antibody (30071-1-AP; 1:400; incubated at room temperature for 1.5 hours) with sh-Control and sh-CUL2 transfected PC-3 cells. This data was developed using the same antibody clone with 30071-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy CUL2 Ready-To-Use IHC Kit. CUL2 primary antibody included.

产品信息

30071-1-PBS targets CUL2 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen CUL2 fusion protein Ag32331 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name cullin 2
Synonyms
Calculated Molecular Weight 87 kDa
Observed Molecular Weight 80-87 kDa
GenBank Accession NumberBC009591
Gene Symbol CUL2
Gene ID (NCBI) 8453
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ13617
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The cullin family proteins are scaffold proteins for the Ring finger type E3 ligases, participating in the proteolysis through the ubiquitin-proteasome pathway. Humans express seven cullin proteins: CUL1-3, CUL4A, CUL4B, CUL5, and CUL7. Each cullin protein can form an E3 ligase similar to the prototype Ring-type E3 ligase Skp1-CUL1-F-box complex. The Cullin-RING-finger type E3 ligases are important regulators in early embryonic development, as highlighted by genetic studies demonstrating that knock-out of CUL1, CUL3, or CUL4A in mice results in early embryonic lethality.