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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • IF Staining of mouse kidney using 29819-1-AP (same clone as 29819-1-PBS)

    IF Staining of mouse kidney using 29819-1-AP (same clone as 29819-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse kidney tissue using CX3CR1 antibody (29819-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 29819-1-PBS in a different storage buffer formulation.

  • WB analysis using 29819-1-AP (same clone as 29819-1-PBS)

    WB analysis using 29819-1-AP (same clone as 29819-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 29819-1-AP (CX3CR1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29819-1-PBS in a different storage buffer formulation.

CX3CR1 Polyclonal antibody, PBS Only

CX3CR1 Polyclonal Antibody for WB, IF-P, Indirect ELISA
Cat No. 29819-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IF-P, Indirect ELISA

Synonyms

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

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产品信息

29819-1-PBS targets CX3CR1 in WB, IF-P, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IF-P, Indirect ELISA Application Description
Tested Reactivity human
Immunogen CX3CR1 fusion protein Ag27698 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name chemokine (C-X3-C motif) receptor 1
Synonyms
Calculated Molecular Weight 40 kDa
Observed Molecular Weight40 kDa, 44 kDa
GenBank Accession NumberBC028078
Gene Symbol CX3CR1
Gene ID (NCBI) 1524
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP49238
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CX3CR1, also known as GPR13, V28 and fractalkine receptor, belongs to the 7-transmembrane G protein-coupled receptor (GPCR) family. It is expressed on microglia, astrocytes, NK cells, monocytes/macrophages, and a subpopulation of T cells. CX3CR1 is the receptor for fractalkine (CX3CL1) and mediates both its adhesive and migratory functions. It also acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro), and some variations in the gene of CX3CR1 lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Defects in CX3CR1 are a cause of susceptibility to age-related macular degeneration type 12 (ARMD12). The two CX3CR1 bands exhibited can be attributed to various factors (PMID: 30628679).