验证数据展示
经过测试的应用
| Positive FC (Intra) detected in | LPS and Brefeldin A treated mouse splenocytes |
For other applications, we recommend the unconjugated version of this antibody, 98047-1-PBS
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL647-98047 targets CXCL1 in FC (Intra) applications and shows reactivity with mouse samples.
| 经测试应用 | FC (Intra) Application Description |
| 经测试反应性 | mouse |
| 免疫原 | Fusion Protein 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | chemokine (C-X-C motif) ligand 1 |
| 别名 | Growth-regulated alpha protein, chemokine (C X C motif) ligand 1, 240268D2 |
| 计算分子量 | 10kd |
| GenBank蛋白编号 | NM_008176 |
| 基因名称 | Cxcl1 |
| Gene ID (NCBI) | 14825 |
| RRID | AB_3673679 |
| 偶联类型 | CoraLite® Plus 647 Fluorescent Dye |
| 最大激发/发射波长 | 654 nm / 674 nm |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P12850-1 |
| 储存缓冲液 | PBS with 0.09% sodium azide , pH 7.3 |
| 储存条件 | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
CXCL1 a is a member of CXC family and also known as keratinocyte-derived chemokines (KC) or growth-related oncogene (GRO). CXCL1 is expressed by macrophages, neutrophils and epithelial cells. CXCL1 binding specifically to the CXC chemokine receptor CXCR2, is involved in fibrogenesis and angiogenesis. This protein also plays a role in inflammation and as a chemoattractant for neutrophils. CXCL1 is upregulated in some types of human cancer, including colorectal, bladder, breast, prostate and skin cancers.
实验方案
| Product Specific Protocols | |
|---|---|
| FC protocol for CL Plus 647 CXCL1 antibody CL647-98047 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |