• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

CXCR5 Recombinant antibody, PBS Only

CXCR5 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241777A10

Cat no : 84639-2-PBS

Print datasheet

Synonyms

CXCR 5, CXC R5, CD185, Burkitt lymphoma receptor 1, BLR1

验证数据展示

  • WB analysis using 84639-2-RR (same clone as 84639-2-PBS)

    WB analysis using 84639-2-RR (same clone as 84639-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84639-2-RR (CXCR5 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84639-2-PBS in a different storage buffer formulation.

产品信息

84639-2-PBS targets CXCR5 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name chemokine (C-X-C motif) receptor 5
Synonyms CXCR 5, CXC R5, CD185, Burkitt lymphoma receptor 1, BLR1
Calculated Molecular Weight 372 aa, 42 kDa
Observed Molecular Weight33 kDa
GenBank Accession NumberBC110352
Gene Symbol CXCR5
Gene ID (NCBI) 643
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP32302
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Initially discovered in 1992 as Burkitt's lymphoma receptor 1, CXCR5 (chemokine receptor 5, also known as CD185) is a seven-transmembrane G protein-coupled receptor (GPCR) protein (PMID: 32994482). CXCR5 is essential for naïve B-cell migration to and maturation in the lymph nodes and spleen, as well as for cluster of differentiation 4 T-cell (TFH and TCM) homing and interaction with B cells (PMID: 21471443). Moreover, CXCR5 is involved in the regulation of neural stem cells (NSC) and neuronal regeneration in the mouse brain, neuronal differentiation, neurogenesis, gliogenesis, and synaptogenesis (PMID: 37460877).