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CXCR7 Monoclonal antibody, PBS Only

CXCR7 Monoclonal Antibody for WB, IHC, IF-P, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

human, mouse

Applications

WB, IHC, IF-P, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

4C3D7

Cat no : 60216-1-PBS

Print datasheet

Synonyms

ACKR3, Chemokine orphan receptor 1, CMKOR1, CXC R7, CXCR 7, CXCR7, G protein coupled receptor 159, GPR159, RDC 1, RDC1

验证数据展示

  • WB analysis using 60216-1-Ig (same clone as 60216-1-PBS)

    WB analysis using 60216-1-Ig (same clone as 60216-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 60216-1-Ig (CXCR7 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control. This data was developed using the same antibody clone with 60216-1-PBS in a different storage buffer formulation.

  • IF Staining of human prostate cancer using 60216-1-Ig (same clone as 60216-1-PBS)

    IF Staining of human prostate cancer using 60216-1-Ig (same clone as 60216-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human prostate cancer tissue using CXCR7 antibody (60216-1-Ig, Clone: 4C3D7 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 60216-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 60216-1-Ig (same clone as 60216-1-PBS)

    IHC staining of human breast cancer using 60216-1-Ig (same clone as 60216-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 60216-1-Ig (CXCR7 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60216-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 60216-1-Ig (same clone as 60216-1-PBS)

    IHC staining of human breast cancer using 60216-1-Ig (same clone as 60216-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 60216-1-Ig (CXCR7 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60216-1-PBS in a different storage buffer formulation.

  • IF Staining of human breast cancer using 60216-1-Ig (same clone as 60216-1-PBS)

    IF Staining of human breast cancer using 60216-1-Ig (same clone as 60216-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human breast cancer tissue using CXCR7 antibody (60216-1-Ig, Clone: 4C3D7 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 60216-1-PBS in a different storage buffer formulation.

  • IF Staining of human breast cancer using 60216-1-Ig (same clone as 60216-1-PBS)

    IF Staining of human breast cancer using 60216-1-Ig (same clone as 60216-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human breast cancer tissue using CXCR7 antibody (60216-1-Ig, Clone: 4C3D7 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 60216-1-PBS in a different storage buffer formulation.

产品信息

60216-1-PBS targets CXCR7 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, IHC, IF-P, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen CXCR7 fusion protein Ag14247 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name chemokine (C-X-C motif) receptor 7
Synonyms ACKR3, Chemokine orphan receptor 1, CMKOR1, CXC R7, CXCR 7, CXCR7, G protein coupled receptor 159, GPR159, RDC 1, RDC1
Calculated Molecular Weight 362 aa, 41 kDa
Observed Molecular Weight 50-60 kDa
GenBank Accession NumberBC036661
Gene Symbol CXCR7
Gene ID (NCBI) 57007
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP25106
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CXCR7 (C-X-C chemokine receptor type 7), also known as RDC1, is a member of the G-protein coupled receptor family. CXCR7 can bind the chemokines CXCL11 and CXCL12 with high affinity, and it also acts as a coreceptor with CXCR4 for a restricted number of HIV isolates. Expression of CXCR7 has been associated with cardiac development as well as with tumor growth and progression. This antibody recognizes endogenous CXCR7, which has an experimentally determined molecular weight of 50 kDa (PMID: 20197403; 20388803).