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Host
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Species Reactivity
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Species Reactivity
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Conjugate
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Compatible Species
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Conjugate
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验证数据展示

  • WB analysis using 60216-1-Ig (same clone as 60216-1-PBS)

    WB analysis using 60216-1-Ig (same clone as 60216-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 60216-1-Ig (CXCR7 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control. This data was developed using the same antibody clone with 60216-1-PBS in a different storage buffer formulation.

  • IF Staining of human prostate cancer using 60216-1-Ig (same clone as 60216-1-PBS)

    IF Staining of human prostate cancer using 60216-1-Ig (same clone as 60216-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human prostate cancer tissue using CXCR7 antibody (60216-1-Ig, Clone: 4C3D7 ) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 60216-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 60216-1-Ig (same clone as 60216-1-PBS)

    IHC staining of human breast cancer using 60216-1-Ig (same clone as 60216-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 60216-1-Ig (CXCR7 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60216-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 60216-1-Ig (same clone as 60216-1-PBS)

    IHC staining of human breast cancer using 60216-1-Ig (same clone as 60216-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 60216-1-Ig (CXCR7 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60216-1-PBS in a different storage buffer formulation.

  • IF Staining of human breast cancer using 60216-1-Ig (same clone as 60216-1-PBS)

    IF Staining of human breast cancer using 60216-1-Ig (same clone as 60216-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human breast cancer tissue using CXCR7 antibody (60216-1-Ig, Clone: 4C3D7 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 60216-1-PBS in a different storage buffer formulation.

  • IF Staining of human breast cancer using 60216-1-Ig (same clone as 60216-1-PBS)

    IF Staining of human breast cancer using 60216-1-Ig (same clone as 60216-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human breast cancer tissue using CXCR7 antibody (60216-1-Ig, Clone: 4C3D7 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 60216-1-PBS in a different storage buffer formulation.

CXCR7 Monoclonal antibody, PBS Only

CXCR7 Monoclonal Antibody for WB, IHC, IF-P, Indirect ELISA
Cat No. 60216-1-PBS

产品说明书

CloneNo. 4C3D7

宿主/亚型

Mouse / IgG2b

种属反应性

human, mouse

应用

WB, IHC, IF-P, Indirect ELISA

别名

ACKR3, CXC R7, C-X-C chemokine receptor type 7, CMKOR1, Chemokine orphan receptor 1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

60216-1-PBS targets CXCR7 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, IF-P, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 CXCR7 fusion protein Ag14247 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 chemokine (C-X-C motif) receptor 7
别名 ACKR3, CXC R7, C-X-C chemokine receptor type 7, CMKOR1, Chemokine orphan receptor 1
计算分子量 362 aa, 41 kDa
观测分子量 50-60 kDa
GenBank蛋白编号BC036661
基因名称 CXCR7
Gene ID (NCBI) 57007
RRIDAB_11182925
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP25106
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CXCR7 (C-X-C chemokine receptor type 7), also known as RDC1, is a member of the G-protein coupled receptor family. CXCR7 can bind the chemokines CXCL11 and CXCL12 with high affinity, and it also acts as a coreceptor with CXCR4 for a restricted number of HIV isolates. Expression of CXCR7 has been associated with cardiac development as well as with tumor growth and progression. This antibody recognizes endogenous CXCR7, which has an experimentally determined molecular weight of 50 kDa (PMID: 20197403; 20388803).