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CXXC5 Recombinant antibody, PBS Only

CXXC5 Uni-rAbTM Recombinant Antibody for IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241034E6

Cat no : 83940-6-PBS

Print datasheet

Synonyms

Putative MAPK-activating protein PM08, HSPC195, CXXC-type zinc finger protein 5, CXXC finger 5, CF5

验证数据展示

  • IF Staining of HepG2 using 83940-6-RR (same clone as 83940-6-PBS)

    IF Staining of HepG2 using 83940-6-RR (same clone as 83940-6-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using CXXC5 antibody (83940-6-RR, Clone: 241034E6 ) at dilution of 1:250 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 83940-6-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83940-6-RR

    Affinity and Kinetic Characterization of 83940-6-RR

    Biolayer interferometry (BLl) kinetic assays of 83940-6-RR against Human CXXC5 were performed. The affinity constant is 6.36 nM.

Planning an IHC experiment? We recommend our IHCeasy CXXC5 Ready-To-Use IHC Kit. CXXC5 primary antibody included.

产品信息

83940-6-PBS targets CXXC5 in IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications IF/ICC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen CXXC5 fusion protein Ag9733 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name CXXC finger 5
Synonyms Putative MAPK-activating protein PM08, HSPC195, CXXC-type zinc finger protein 5, CXXC finger 5, CF5
Calculated Molecular Weight322aa,33 kDa; 227aa,24 kDa
GenBank Accession NumberBC017439
Gene Symbol CXXC5
Gene ID (NCBI) 51523
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ7LFL8
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CXXC5 (CXXC-type zinc finger protein 5) is also named as HSPC195, RINF and TCCCIA00297.CXXC5 is a member of the CXXC-type zinc-finger protein family. CXXC5 is a short protein (322 amino acids in length) that does not have any catalytic domain, but is able to bind to DNA and act as a transcription factor and epigenetic factor through protein-protein interactions. In addition, CXXC5 is capable of regulating various signal transduction processes, including the TGF-β, Wnt and ATM-p53 pathways, thereby acting as a novel and crucial signaling coordinator. CXXC5 plays an important role in embryonic development and adult tissue homeostasis by regulating cell proliferation, differentiation and apoptosis (PMID: 30479059). CXXC5 has two isoforms of 33 kDa and 24 kDa (PMID: 25805812). CXXC5 is modified by phosphorylation after translation.