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验证数据展示

  • IF Staining of HepG2 using 83940-6-RR

    IF Staining of HepG2 using 83940-6-RR

    Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using CXXC5 antibody (83940-6-RR, Clone: 241034E6 ) at dilution of 1:250 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red).

  • Affinity and Kinetic Characterization of 83940-6-RR

    Affinity and Kinetic Characterization of 83940-6-RR

    Biolayer interferometry (BLl) kinetic assays of 83940-6-RR against Human CXXC5 were performed. The affinity constant is 6.36 nM.

CXXC5 Recombinant antibody

CXXC5 Uni-rAbTM Recombinant Antibody for IF/ICC, ELISA
Cat No. 83940-6-RR

产品说明书

CloneNo. 241034E6

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IF/ICC, ELISA

别名

Putative MAPK-activating protein PM08, HSPC195, CXXC-type zinc finger protein 5, CXXC finger 5, CF5

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive IF/ICC detected inHepG2 cells
Planning an IHC experiment? We recommend our IHCeasy CXXC5 Ready-To-Use IHC Kit. CXXC5 primary antibody included.

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)/ICCIF/ICC : 1:125-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

83940-6-RR targets CXXC5 in IF/ICC, ELISA applications and shows reactivity with human samples.

经测试应用 IF/ICC, ELISA Application Description
经测试反应性 human
免疫原 CXXC5 fusion protein Ag9733 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CXXC finger 5
别名 Putative MAPK-activating protein PM08, HSPC195, CXXC-type zinc finger protein 5, CXXC finger 5, CF5
计算分子量322aa,33 kDa; 227aa,24 kDa
GenBank蛋白编号BC017439
基因名称 CXXC5
Gene ID (NCBI) 51523
RRIDAB_3671521
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ7LFL8
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

CXXC5 (CXXC-type zinc finger protein 5) is also named as HSPC195, RINF and TCCCIA00297.CXXC5 is a member of the CXXC-type zinc-finger protein family. CXXC5 is a short protein (322 amino acids in length) that does not have any catalytic domain, but is able to bind to DNA and act as a transcription factor and epigenetic factor through protein-protein interactions. In addition, CXXC5 is capable of regulating various signal transduction processes, including the TGF-β, Wnt and ATM-p53 pathways, thereby acting as a novel and crucial signaling coordinator. CXXC5 plays an important role in embryonic development and adult tissue homeostasis by regulating cell proliferation, differentiation and apoptosis (PMID: 30479059). CXXC5 has two isoforms of 33 kDa and 24 kDa (PMID: 25805812). CXXC5 is modified by phosphorylation after translation.

实验方案

Product Specific Protocols
IF protocol for CXXC5 antibody 83940-6-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols