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验证数据展示

  • IF Staining of Jurkat using 83845-3-RR (same clone as 83845-3-PBS)

    IF Staining of Jurkat using 83845-3-RR (same clone as 83845-3-PBS)

    Immunofluorescent analysis of (4% PFA) fixed Jurkat cells using CYFIP2 antibody (83845-3-RR, Clone: 240909E3 ) at dilution of 1:250 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 83845-3-PBS in a different storage buffer formulation.

  • FC experiment of Jurkat using 83845-3-RR (same clone as 83845-3-PBS)

    FC experiment of Jurkat using 83845-3-RR (same clone as 83845-3-PBS)

    1x10^6 Jurkat cells were intracellularly stained with 0.25 ug Cyfip2 Recombinant Antibody (83845-3-RR, Clone:240909E3) and APC-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)(red), or 0.25 ug Isotype Control (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 83845-3-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83845-3-RR

    Affinity and Kinetic Characterization of 83845-3-RR

    Biolayer interferometry (BLl) kinetic assays of 83845-3-RR against Human CYFIP2 were performed. The affinity constant is 4.35 nM.

CYFIP2 Recombinant antibody, PBS Only

CYFIP2 Uni-rAbTM Recombinant Antibody for IF/ICC, FC (Intra), ELISA
Cat No. 83845-3-PBS

产品说明书

CloneNo. 240909E3

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IF/ICC, FC (Intra), ELISA

别名

CYFIP1/2, 240909E3, p53-inducible protein 121, p53 inducible protein 121, KIAA1168

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy CYFIP2 Ready-To-Use IHC Kit. CYFIP2 primary antibody included.

产品信息

83845-3-PBS targets CYFIP2 in IF/ICC, FC (Intra), ELISA applications and shows reactivity with human samples.

经测试应用 IF/ICC, FC (Intra), ELISA Application Description
经测试反应性 human
免疫原 CYFIP2 fusion protein Ag8749 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 cytoplasmic FMR1 interacting protein 2
别名 CYFIP1/2, 240909E3, p53-inducible protein 121, p53 inducible protein 121, KIAA1168
计算分子量 148 kDa
GenBank蛋白编号BC011762
基因名称 CYFIP2
Gene ID (NCBI) 26999
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ96F07
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CYFIP1/2 belongs to the CYFIP family and is involved in T-cell adhesion and p53-dependent induction of apoptosis. CYFIP1 contains 1,253 amino acids and shares 88% sequence identity with CYFIP2. CYFIP1 and CYFIP2 are members of a highly conserved protein family and share approximately 99% sequence identity with their mouse orthologs. CYFIP1 has been shown to interact with the small GTPase RAC1, which is implicated in development and maintenance of neuronal structures. Consistent with FMRP and RAC1 localization in dendritic fine structures, CYFIP1/2 are present in synaptosomal extracts. This antibody can recognize both CYFIP1 and CYFIP2.