验证数据展示
产品信息
67033-1-PBS targets CYP1B1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig samples.
Tested Applications | WB, IHC, Indirect ELISA Application Description |
Tested Reactivity | human, mouse, rat, pig |
Immunogen | CYP1B1 fusion protein Ag13380 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | cytochrome P450, family 1, subfamily B, polypeptide 1 |
Synonyms | GLC3A, EC:4.2.1.152, EC:1.14.14.1, CYPIB1, CP1B |
Calculated Molecular Weight | 61 kDa |
Observed Molecular Weight | 52 kDa |
GenBank Accession Number | BC012049 |
Gene Symbol | CYP1B1 |
Gene ID (NCBI) | 1545 |
RRID | AB_2882348 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q16678 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Cytochrome P450 CYP1B1 is a recently cloned dioxin-inducible form of the cytochrome P450 family of xenobiotic metabolizing enzymes. CYP1B1 was found to be expressed at a high frequency in a wide range of human cancers of different histogenetic types, including cancers of the breast, colon, lung, esophagus, skin, lymph node, brain, and testis. There was no detectable immunostaining for CYP1B1 in normal tissues.(PMID:9230218). CYP1B1 is a 60 kDa protein that it also can be detected a band of 51 kDa or 57 kDa through the western blot(PMID:9525272; PMID: 9525272).