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验证数据展示

  • WB analysis of mouse liver using 14739-1-AP (same clone as 14739-1-PBS)

    WB analysis of mouse liver using 14739-1-AP (same clone as 14739-1-PBS)

    mouse liver tissue were subjected to SDS PAGE followed by western blot with 14739-1-AP (CYP27A1 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14739-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 14739-1-AP (same clone as 14739-1-PBS)

    IHC staining of human liver cancer using 14739-1-AP (same clone as 14739-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 14739-1-AP (CYP27A1 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14739-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CYP27A1 antibody included
  • IHC staining of human liver cancer using 14739-1-AP (same clone as 14739-1-PBS)

    IHC staining of human liver cancer using 14739-1-AP (same clone as 14739-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 14739-1-AP (CYP27A1 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14739-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CYP27A1 antibody included

CYP27A1 Polyclonal antibody, PBS Only

CYP27A1 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 14739-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

Cytochrome P450 27, Cytochrome P 450C27/25, CYP27, CTX, CP27

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy CYP27A1 Ready-To-Use IHC Kit. CYP27A1 primary antibody included.

产品信息

14739-1-PBS targets CYP27A1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 CYP27A1 fusion protein Ag6408 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 cytochrome P450, family 27, subfamily A, polypeptide 1
别名 Cytochrome P450 27, Cytochrome P 450C27/25, CYP27, CTX, CP27
计算分子量 60 kDa
观测分子量 60-65 kDa
GenBank蛋白编号BC051851
基因名称 CYP27A1
Gene ID (NCBI) 1593
RRIDAB_2089276
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ02318
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Mitochondrial sterol 27-hydroxylase (CYP27A1) catalyzes oxidative cleavage of the sterol side chain in the bile acid biosynthetic pathway in the liver and 27-hydroxylation of cholesterol in most tissues(PMID:17088262). It belongs to the cytochrome P450 family. CYP27A1 catalyses an important sterol elimination pathway in the macrophage, and consequently may protect against atherosclerosis.