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验证数据展示

  • IHC staining of human liver cancer using 60297-1-Ig (same clone as 60297-1-PBS)

    IHC staining of human liver cancer using 60297-1-Ig (same clone as 60297-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 60297-1-Ig (CYP2D6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60297-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CYP2D6 antibody included
  • IHC staining of human liver cancer using 60297-1-Ig (same clone as 60297-1-PBS)

    IHC staining of human liver cancer using 60297-1-Ig (same clone as 60297-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 60297-1-Ig (CYP2D6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60297-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CYP2D6 antibody included
  • WB analysis of HepG2 using 60297-1-Ig (same clone as 60297-1-PBS)

    WB analysis of HepG2 using 60297-1-Ig (same clone as 60297-1-PBS)

    HepG2 cells were subjected to SDS PAGE followed by western blot with 60297-1-Ig (CYP2D6 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60297-1-PBS in a different storage buffer formulation.

CYP2D6 Monoclonal antibody, PBS Only

CYP2D6 Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 60297-1-PBS

产品说明书

CloneNo. 8B11D12

宿主/亚型

Mouse / IgG2b

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

CPD6, CYP2D, CYP2D@, CYP2D6, CYP2DL1, Cytochrome P450 2D6, P450 DB1, P450C2D, P450DB1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy CYP2D6 Ready-To-Use IHC Kit. CYP2D6 primary antibody included.

产品信息

60297-1-PBS targets CYP2D6 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 CYP2D6 fusion protein Ag12605 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 cytochrome P450, family 2, subfamily D, polypeptide 6
别名 CPD6, CYP2D, CYP2D@, CYP2D6, CYP2DL1, Cytochrome P450 2D6, P450 DB1, P450C2D, P450DB1
计算分子量 497 aa, 56 kDa
观测分子量 56 kDa
GenBank蛋白编号BC075023
基因名称 CYP2D6
Gene ID (NCBI) 1565
RRIDAB_2881412
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP10635
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CYP2D6(Cytochrome P450 2D6) is also named as CYP2DL1 and belongs to the cytochrome P450 family. It is a monooxygenase that involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants. CYP2D6 is responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It has 2 isoforms produced by alternative splicing with the molecular weight of 56 kDa and 50 kDa.