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CYP2D6 Monoclonal antibody, PBS Only

CYP2D6 Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

8B11D12

Cat no : 60297-1-PBS

Print datasheet

Synonyms

CPD6, CYP2D, CYP2D@, CYP2D6, CYP2DL1, Cytochrome P450 2D6, P450 DB1, P450C2D, P450DB1

验证数据展示

  • IHC staining of human liver cancer using 60297-1-Ig (same clone as 60297-1-PBS)

    IHC staining of human liver cancer using 60297-1-Ig (same clone as 60297-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 60297-1-Ig (CYP2D6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60297-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CYP2D6 antibody included
  • IHC staining of human liver cancer using 60297-1-Ig (same clone as 60297-1-PBS)

    IHC staining of human liver cancer using 60297-1-Ig (same clone as 60297-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 60297-1-Ig (CYP2D6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60297-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CYP2D6 antibody included
  • WB analysis of HepG2 using 60297-1-Ig (same clone as 60297-1-PBS)

    WB analysis of HepG2 using 60297-1-Ig (same clone as 60297-1-PBS)

    HepG2 cells were subjected to SDS PAGE followed by western blot with 60297-1-Ig (CYP2D6 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60297-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy CYP2D6 Ready-To-Use IHC Kit. CYP2D6 primary antibody included.

产品信息

60297-1-PBS targets CYP2D6 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen CYP2D6 fusion protein Ag12605 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name cytochrome P450, family 2, subfamily D, polypeptide 6
Synonyms CPD6, CYP2D, CYP2D@, CYP2D6, CYP2DL1, Cytochrome P450 2D6, P450 DB1, P450C2D, P450DB1
Calculated Molecular Weight 497 aa, 56 kDa
Observed Molecular Weight 56 kDa
GenBank Accession NumberBC075023
Gene Symbol CYP2D6
Gene ID (NCBI) 1565
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP10635
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CYP2D6(Cytochrome P450 2D6) is also named as CYP2DL1 and belongs to the cytochrome P450 family. It is a monooxygenase that involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants. CYP2D6 is responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It has 2 isoforms produced by alternative splicing with the molecular weight of 56 kDa and 50 kDa.