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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 31020-1-AP (same clone as 31020-1-PBS)

    WB analysis using 31020-1-AP (same clone as 31020-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31020-1-AP (Casp1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31020-1-PBS in a different storage buffer formulation.

Mouse Caspase 1 Polyclonal antibody, PBS Only

Caspase 1 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 31020-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

mouse, rat

Applications

WB, Indirect ELISA

Synonyms

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated

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产品信息

31020-1-PBS targets Caspase 1 in WB, Indirect ELISA applications and shows reactivity with mouse, rat samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity mouse, rat
Immunogen Caspase 1 fusion protein Ag34441 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name caspase 1
Synonyms
Observed Molecular Weight35-40 kDa
GenBank Accession NumberBC008152
Gene Symbol Caspase 1
Gene ID (NCBI) 12362
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity Purification
UNIPROT IDP29452
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CASP1(caspase-1) is also named as IL1BC, IL1BCE and belongs to the peptidase C14A family. It is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta (IL1B), IL18, and IL33 precursor proteins. The active caspase-1 can increase cellular membrane permeability and intracellular calcium levels, which facilitates lysosome exocytosis and release of host antimicrobial factors and microbial products (PMID:21804020). 31020-1-AP is designed for mouse caspase 1.