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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 31020-1-AP (same clone as 31020-1-PBS)

    WB analysis using 31020-1-AP (same clone as 31020-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31020-1-AP (Casp1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31020-1-PBS in a different storage buffer formulation.

Mouse Caspase 1 Polyclonal antibody, PBS Only

Caspase 1 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 31020-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

mouse, rat

应用

WB, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

31020-1-PBS targets Caspase 1 in WB, Indirect ELISA applications and shows reactivity with mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 mouse, rat
免疫原 Caspase 1 fusion protein Ag34441 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 caspase 1
别名
观测分子量35-40 kDa
GenBank蛋白编号BC008152
基因名称 Caspase 1
Gene ID (NCBI) 12362
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity Purification
UNIPROT IDP29452
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CASP1(caspase-1) is also named as IL1BC, IL1BCE and belongs to the peptidase C14A family. It is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta (IL1B), IL18, and IL33 precursor proteins. The active caspase-1 can increase cellular membrane permeability and intracellular calcium levels, which facilitates lysosome exocytosis and release of host antimicrobial factors and microbial products (PMID:21804020). 31020-1-AP is designed for mouse caspase 1.