Caspase 2/p32/p18 Monoclonal antibody, PBS Only
Caspase 2/p32/p18 Monoclonal Antibody for WB,Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human
Applications
WB,Indirect ELISA
Conjugate
Unconjugated
CloneNo.
2G4C2
验证数据展示
Planning an IHC experiment? We recommend our IHCeasy Caspase 2 Ready-To-Use IHC Kit. Caspase 2 primary antibody included.
产品信息
66517-1-PBS targets Caspase 2/p32/p18 in WB, Indirect ELISA applications and shows reactivity with Human samples.
Tested Applications | WB,Indirect ELISA Application Description |
Tested Reactivity | Human |
Immunogen | Caspase 2/p32/p18 fusion protein Ag20141 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | caspase 2, apoptosis-related cysteine peptidase |
Synonyms | CASP 2, CASP2, Caspase 2, Caspase 2/p32/p18, Caspase2, ICH 1L, ICH 1L/1S, ICH1, NEDD 2, NEDD2, Protease ICH 1 |
Calculated Molecular Weight | 452 aa, 51 kDa |
Observed Molecular Weight | 48-51 kDa, 32 kDa, 18 kDa |
GenBank Accession Number | BC002427 |
Gene Symbol | CASP2 |
Gene ID (NCBI) | 835 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | P42575 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
背景介绍
CASP2(Caspase-2) is also named as ICH1, NEDD2 and belongs to the peptidase C14A family.It is involved in the activation cascade of caspases responsible for apoptosis execution and might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.It has 2 isoforms produced by alternative splicing and can exists almost as a dimer in solution(PMID:15865942).This antibody can recognize the 32 kDa pro-caspase 2 as well as 18 kDa cleaved-caspase 2.