验证数据展示
产品信息
68433-1-PBS targets Centrin 1 in IF/ICC, Indirect ELISA applications and shows reactivity with Human samples.
经测试应用 | IF/ICC, Indirect ELISA Application Description |
经测试反应性 | Human |
免疫原 | Centrin 1 fusion protein Ag3529 种属同源性预测 |
宿主/亚型 | Mouse / IgG2b |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | centrin, EF-hand protein, 1 |
别名 | Caltractin isoform 2, CEN1, Centrin 1, centrin, EF hand protein, 1, CETN, CETN1 |
计算分子量 | 172 aa, 20 kDa |
观测分子量 | 20 kDa |
GenBank蛋白编号 | BC029515 |
基因名称 | Centrin 1 |
Gene ID (NCBI) | 1068 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q12798 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
EF-hand type Ca2+-binding proteins consists of several family members, including Centrin-1, Centrin-2 and Centrin-3. The Centrin proteins are ubiquitously expressed cytoskeletal components that show increased expression during cell differentiation. Centrin-1 plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. Centrin-1 is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle.