Collagen Type VI Monoclonal antibody
Collagen Type VI Monoclonal Antibody for WB, ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
Human
Applications
WB, ELISA
Conjugate
Unconjugated
CloneNo.
3E9C2
验证数据展示
经过测试的应用
Positive WB detected in | human placenta tissue, human heart tissue |
Planning an IHC experiment? We recommend our IHCeasy COL6A2 Ready-To-Use IHC Kit. COL6A2 primary antibody included.
推荐稀释比
Application | Dilution |
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Western Blot (WB) | WB : 1:5000-1:50000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
68652-1-Ig targets Collagen Type VI in WB, ELISA applications and shows reactivity with Human samples.
Tested Applications | WB, ELISA Application Description |
Tested Reactivity | Human |
Immunogen | Collagen Type VI fusion protein Ag7134 种属同源性预测 |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Full Name | collagen, type VI, alpha 2 |
Synonyms | COL6A2, Collagen alpha 2(VI) chain, collagen, type VI, alpha 2, DKFZp586E1322, FLJ46862, PP3610 |
Calculated Molecular Weight | 109 kDa |
Observed Molecular Weight | 140 kDa |
GenBank Accession Number | BC065509 |
Gene Symbol | COL6A2 |
Gene ID (NCBI) | 1292 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P12110 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Collagen VI, composed of three polypeptides, alpha-1(VI), alpha-2(VI), and alpha-3(VI) chains, is a beaded filament collagen found in most connective tissues. The alpha-1(VI) and alpha-2(VI) chains are 140 kDa, while the alpha-3(VI) chain is 200-300 kDa (PMID: 3792302, 3348212). COL6A2 gene encodes the alpha-2 subunit of type VI collagen. The alpha-2(VI) subunit has a calculated molecular weight of 109 kDa, and an apparent molecular weight of 140 kDa due to posttranslational modification. Mutations in COL6A2 gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene.
实验方案
Product Specific Protocols | |
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WB protocol for Collagen Type VI antibody 68652-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |