Collagen Type VI Monoclonal antibody, PBS Only

Collagen Type VI Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

Human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3E9C2

Cat no : 68652-1-PBS

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Synonyms

COL6A2, Collagen alpha 2(VI) chain, collagen, type VI, alpha 2, DKFZp586E1322, FLJ46862, PP3610



Planning an IHC experiment? We recommend our IHCeasy COL6A2 Ready-To-Use IHC Kit. COL6A2 primary antibody included.

产品信息

68652-1-PBS targets Collagen Type VI in WB, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human
Immunogen Collagen Type VI fusion protein Ag7134 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name collagen, type VI, alpha 2
Synonyms COL6A2, Collagen alpha 2(VI) chain, collagen, type VI, alpha 2, DKFZp586E1322, FLJ46862, PP3610
Calculated Molecular Weight 109 kDa
Observed Molecular Weight140 kDa
GenBank Accession NumberBC065509
Gene Symbol COL6A2
Gene ID (NCBI) 1292
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP12110
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Collagen VI, composed of three polypeptides, alpha-1(VI), alpha-2(VI), and alpha-3(VI) chains, is a beaded filament collagen found in most connective tissues. The alpha-1(VI) and alpha-2(VI) chains are 140 kDa, while the alpha-3(VI) chain is 200-300 kDa (PMID: 3792302, 3348212). COL6A2 gene encodes the alpha-2 subunit of type VI collagen. The alpha-2(VI) subunit has a calculated molecular weight of 109 kDa, and an apparent molecular weight of 140 kDa due to posttranslational modification. Mutations in COL6A2 gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene.