验证数据展示
产品信息
67048-1-PBS targets Cyclin D2 in WB, Indirect ELISA applications and shows reactivity with Human, mouse samples.
| Tested Applications | WB, Indirect ELISA Application Description |
| Tested Reactivity | Human, mouse |
| Immunogen | Cyclin D2 fusion protein Ag25190 种属同源性预测 |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | cyclin D2 |
| Synonyms | CCND2, cyclin D, cyclin D2, G1/S specific cyclin D2, KIAK0002 |
| Calculated Molecular Weight | 32 kDa |
| Observed Molecular Weight | 30 kDa |
| GenBank Accession Number | BC010958 |
| Gene Symbol | Cyclin D2 |
| Gene ID (NCBI) | 894 |
| RRID | AB_2882361 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P30279 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CCND2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. CCND2 forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. CCND2 has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. High level expression of CCND2 was observed in ovarian and testicular tumors.
