Cyclin G Polyclonal antibody

Cyclin G Polyclonal Antibody for WB, ELISA
Cat No. 29306-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

Human and More (1)

应用

WB, ELISA and More (1)

CCNG, CCNG1, CYCG1, Cyclin G, cyclin G1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inMDA-MB-231 cells, MDA-MB-453s cells, T-47D cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

29306-1-AP targets Cyclin G in WB, IF, ELISA applications and shows reactivity with Human samples.

经测试应用 WB, ELISA Application Description
文献引用应用WB, IF
经测试反应性 Human
文献引用反应性mouse
免疫原 Cyclin G fusion protein Ag30937 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 cyclin G1
别名 CCNG, CCNG1, CYCG1, Cyclin G, cyclin G1
计算分子量 34 kDa
观测分子量 34 kDa
GenBank蛋白编号BC007093
基因名称 Cyclin G
Gene ID (NCBI) 900
RRIDAB_3086111
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP51959
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Cyclin G is also named as CCNG, CYCG1 and CCNG1, and and belongs to the cyclin family. Cyclin G may play a role in growth regulation. Cyclin G is associated with G2/M phase arrest in response to DNA damage. And it may be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation, and levels of Cyclin G are increased after induction of p53 by DNA damage (PMID:12015958). Cyclin G is high levels in skeletal muscle, ovary, kidney and colon. Cyclin G is very low levels in normal cells during G1 phase, which increase as cells enter the S phase and stay high throughout the S and G2/M phases. In breast cancer cells, consistent high levels of Cyclin G are found throughout the cell cycle (PMID:11063931).

实验方案

Product Specific Protocols
WB protocol for Cyclin G antibody 29306-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseWB,IF

Biomolecules

Cyclin G1 Regulates the Alveolarization in Models of Bronchopulmonary Dysplasia by Inhibiting AT2 Cell Proliferation

Authors - Panpan Xu
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