Cyclophilin A Monoclonal antibody, PBS Only

Cyclophilin A Monoclonal Antibody for WB, IF/ICC, FC (Intra), ELISA
Cat No. 67880-1-PBS

产品说明书

CloneNo. 2B11B9

宿主/亚型

Mouse / IgG1

种属反应性

rat, mouse, human

应用

WB, IF/ICC, FC (Intra), ELISA

PPIA, EC:5.2.1.8, CYPH, CYPA, Cyclosporin A-binding protein

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


Planning an IHC experiment? We recommend our IHCeasy PPIA Ready-To-Use IHC Kit. PPIA primary antibody included.

产品信息

67880-1-PBS targets Cyclophilin A in WB, IF/ICC, FC (Intra), ELISA applications and shows reactivity with rat, mouse, human samples.

经测试应用 WB, IF/ICC, FC (Intra), ELISA Application Description
经测试反应性 rat, mouse, human
免疫原 Cyclophilin A fusion protein Ag1120 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 peptidylprolyl isomerase A (cyclophilin A)
别名 PPIA, EC:5.2.1.8, CYPH, CYPA, Cyclosporin A-binding protein
计算分子量 18 kDa
观测分子量18 kDa
GenBank蛋白编号BC005320
基因名称 PPIA
Gene ID (NCBI) 5478
RRIDAB_2918637
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP62937
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Cyclophilin A, also named as PPIA and Rotamase A, belongs to the cyclophilin-type PPIase family and PPIase A subfamily. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIA forms a trimolecular complex with cyclophilin and calcineurins to inhibit calcineurin phosphatase activity. PPIA is incorporated into the virion of the type 1 human immunodeficiency virus (HIV-1) via a direct interaction with the capsid domain of the viral Gag polyprotein and is crucial for efficient viral replication.

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